ClinVar Miner

Variants in gene LRP2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
244 30 8 38 11 0 0 53

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 8 1 0 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 0 0 0 10 4
likely benign 0 0 10 0 37
benign 0 0 4 37 0

All variants with conflicting interpretations #

Total variants: 53
Download table as spreadsheet
HGVS dbSNP
NM_004525.2(LRP2):c.10403C>T (p.Pro3468Leu) rs143367996
NM_004525.2(LRP2):c.10503G>A (p.Gln3501=) rs2229265
NM_004525.2(LRP2):c.11498-13delT rs143342962
NM_004525.2(LRP2):c.11601T>C (p.Cys3867=) rs2229268
NM_004525.2(LRP2):c.11759-5T>G rs76488092
NM_004525.2(LRP2):c.12280A>G (p.Lys4094Glu) rs2075252
NM_004525.2(LRP2):c.13610A>C (p.Gln4537Pro) rs188918037
NM_004525.2(LRP2):c.13685T>C (p.Val4562Ala) rs142245618
NM_004525.2(LRP2):c.2006G>A (p.Gly669Asp) rs34291900
NM_004525.2(LRP2):c.2460A>G (p.Thr820=) rs2241190
NM_004525.2(LRP2):c.2511C>T (p.Ala837=) rs375313914
NM_004525.2(LRP2):c.2640-1G>A rs587776717
NM_004525.2(LRP2):c.3054C>A (p.Thr1018=) rs2075249
NM_004525.2(LRP2):c.3452C>T (p.Pro1151Leu) rs150552608
NM_004525.2(LRP2):c.4875T>C (p.Cys1625=) rs2229267
NM_004525.2(LRP2):c.5859A>G (p.Arg1953=) rs11886219
NM_004525.2(LRP2):c.7626C>G (p.Arg2542=) rs13397109
NM_004525.2(LRP2):c.7894A>G (p.Asn2632Asp) rs17848169
NM_004525.2(LRP2):c.8452+1G>A rs80338748
NM_004525.2(LRP2):c.8516_8519delTTTA (p.Tyr2840Cysfs) rs80338749
NM_004525.2(LRP2):c.8614G>A (p.Ala2872Thr) rs2228171
NM_004525.2(LRP2):c.9484_9485delGT (p.Val3162Leufs) rs80338751
NM_004525.3(LRP2):c.10195C>T (p.Arg3399Ter) rs80338752
NM_004525.3(LRP2):c.1093C>T (p.Arg365Ter) rs80338744
NM_004525.3(LRP2):c.11092G>A (p.Val3698Met) rs34355135
NM_004525.3(LRP2):c.1167T>G (p.Asp389Glu) rs111704488
NM_004525.3(LRP2):c.1172-8G>A rs115371758
NM_004525.3(LRP2):c.11996T>G (p.Val3999Gly) rs79723119
NM_004525.3(LRP2):c.12628A>C (p.Ile4210Leu) rs4667591
NM_004525.3(LRP2):c.13113C>T (p.Ile4371=) rs990626
NM_004525.3(LRP2):c.13155C>T (p.His4385=) rs16856476
NM_004525.3(LRP2):c.1341+2T>G rs80338745
NM_004525.3(LRP2):c.149C>G (p.Thr50Ser) rs114460450
NM_004525.3(LRP2):c.2025C>T (p.Val675=) rs830994
NM_004525.3(LRP2):c.2376T>C (p.Asp792=) rs33954745
NM_004525.3(LRP2):c.248A>G (p.Asn83Ser) rs2229263
NM_004525.3(LRP2):c.3069A>G (p.Thr1023=) rs831043
NM_004525.3(LRP2):c.3660A>G (p.Ala1220=) rs831042
NM_004525.3(LRP2):c.402C>A (p.Pro134=) rs34104660
NM_004525.3(LRP2):c.4046-6T>C rs76714416
NM_004525.3(LRP2):c.4236G>C (p.Arg1412=) rs34915742
NM_004525.3(LRP2):c.5085G>A (p.Ser1695=) rs145384264
NM_004525.3(LRP2):c.5100C>T (p.Ser1700=) rs2302694
NM_004525.3(LRP2):c.5209C>T (p.Leu1737Phe) rs149469954
NM_004525.3(LRP2):c.5293G>A (p.Val1765Met) rs116456291
NM_004525.3(LRP2):c.6035G>A (p.Arg2012Lys) rs4667596
NM_004525.3(LRP2):c.639C>T (p.Asp213=) rs2229266
NM_004525.3(LRP2):c.63G>C (p.Ala21=) rs1559014
NM_004525.3(LRP2):c.7253A>G (p.Glu2418Gly) rs61995915
NM_004525.3(LRP2):c.7564T>C (p.Tyr2522His) rs80338747
NM_004525.3(LRP2):c.775G>C (p.Gly259Arg) rs34693334
NM_004525.3(LRP2):c.923-6G>A rs144147038
NM_004525.3(LRP2):c.92C>T (p.Ala31Val) rs144829356

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