ClinVar Miner

Variants in gene LRP2 with conflicting interpretations "uncertain significance" and "benign"

Submission 1 (uncertain significance) minimum review status: Submission 1 (uncertain significance) method:
Submission 2 (benign) minimum review status: Submission 2 (benign) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 15
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HGVS dbSNP gnomAD frequency
NM_004525.3(LRP2):c.923-6G>A rs144147038 0.00611
NM_004525.3(LRP2):c.8892G>A (p.Arg2964=) rs149148763 0.00557
NM_004525.3(LRP2):c.149C>G (p.Thr50Ser) rs114460450 0.00342
NM_004525.3(LRP2):c.10937G>A (p.Arg3646His) rs142549310 0.00298
NM_004525.3(LRP2):c.1973A>G (p.Tyr658Cys) rs111360923 0.00248
NM_004525.3(LRP2):c.5390A>G (p.Asn1797Ser) rs138070797 0.00234
NM_004525.3(LRP2):c.13685T>C (p.Val4562Ala) rs142245618 0.00201
NM_004525.3(LRP2):c.12725A>G (p.Asp4242Gly) rs35942532 0.00171
NM_004525.3(LRP2):c.5209C>T (p.Leu1737Phe) rs149469954 0.00126
NM_004525.3(LRP2):c.1176C>T (p.Gly392=) rs369145798 0.00070
NM_004525.3(LRP2):c.10165A>G (p.Ile3389Val) rs140272085 0.00055
NM_004525.3(LRP2):c.12296-4G>A rs375166826 0.00009
NM_004525.3(LRP2):c.39C>T (p.Leu13=) rs529649802 0.00002
NM_004525.3(LRP2):c.12125G>A (p.Arg4042His) rs199874294
NM_004525.3(LRP2):c.428-8del rs370823033

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