ClinVar Miner

Variants in gene LRP5 with conflicting interpretations "benign" and "uncertain significance"

Submission 1 (benign) minimum review status: Submission 1 (benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 9
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HGVS dbSNP gnomAD frequency
NM_002335.4(LRP5):c.2124G>A (p.Ser708=) rs140977837 0.00230
NM_002335.4(LRP5):c.3107G>A (p.Arg1036Gln) rs61889560 0.00207
NM_002335.4(LRP5):c.3990G>A (p.Ala1330=) rs147637431 0.00108
NM_002335.4(LRP5):c.2234C>T (p.Ala745Val) rs148550774 0.00083
NM_002335.4(LRP5):c.1413-7T>A rs141889567 0.00077
NM_002335.4(LRP5):c.4511C>T (p.Pro1504Leu) rs201475647 0.00039
NM_002335.4(LRP5):c.3901G>A (p.Ala1301Thr) rs149166384 0.00008
NM_002335.4(LRP5):c.-19del rs763941232
NM_002335.4(LRP5):c.3446T>A (p.Leu1149Gln) rs200389686

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