ClinVar Miner

Variants in gene LRPPRC with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
527 46 0 10 19 0 3 28

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 2 2 0 0
likely pathogenic 2 0 1 0 0
uncertain significance 2 1 0 17 5
likely benign 0 0 17 0 8
benign 0 0 5 8 0

All variants with conflicting interpretations #

Total variants: 28
Download table as spreadsheet
NM_133259.4(LRPPRC):c.1068A>G (p.Gln356=) rs4953042
NM_133259.4(LRPPRC):c.114C>T (p.Ser38=) rs886056063
NM_133259.4(LRPPRC):c.1295A>G (p.Glu432Gly) rs144732922
NM_133259.4(LRPPRC):c.1301G>A (p.Gly434Asp) rs146515622
NM_133259.4(LRPPRC):c.135C>T (p.Ala45=) rs886056061
NM_133259.4(LRPPRC):c.1419T>C (p.Asp473=) rs886056057
NM_133259.4(LRPPRC):c.1582+7A>G rs863225446
NM_133259.4(LRPPRC):c.1928A>G (p.His643Arg) rs148575027
NM_133259.4(LRPPRC):c.1929C>T (p.His643=) rs200017171
NM_133259.4(LRPPRC):c.2210+4A>C rs190007694
NM_133259.4(LRPPRC):c.2385C>T (p.Gly795=) rs886056056
NM_133259.4(LRPPRC):c.246G>A (p.Gln82=) rs6741066
NM_133259.4(LRPPRC):c.2562A>G (p.Val854=) rs4494798
NM_133259.4(LRPPRC):c.2569A>G (p.Arg857Gly) rs200138144
NM_133259.4(LRPPRC):c.2965C>T (p.Arg989Cys) rs199706677
NM_133259.4(LRPPRC):c.3030C>T (p.Asp1010=) rs147000685
NM_133259.4(LRPPRC):c.3034C>T (p.Pro1012Ser) rs113374262
NM_133259.4(LRPPRC):c.3148+12C>T rs199684766
NM_133259.4(LRPPRC):c.3275+7G>A rs111392631
NM_133259.4(LRPPRC):c.3963C>A (p.Tyr1321Ter) rs863224052
NM_133259.4(LRPPRC):c.4128del (p.Glu1377fs) rs759052246
NM_133259.4(LRPPRC):c.4132A>G (p.Ser1378Gly) rs149693840
NM_133259.4(LRPPRC):c.58C>T (p.Leu20Phe) rs184339274
NM_133259.4(LRPPRC):c.64C>G (p.Leu22Val) rs181626399
NM_133259.4(LRPPRC):c.79C>T (p.Leu27Phe) rs116727742
NM_133259.4(LRPPRC):c.7G>A (p.Ala3Thr) rs200686732
NM_133259.4(LRPPRC):c.864+2T>C rs863224053
NM_133259.4(LRPPRC):c.96C>T (p.Gly32=) rs886056064

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