ClinVar Miner

Variants in gene MAGI2 with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
298 20 0 16 10 0 0 24

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 10 2
likely benign 10 0 16
benign 2 16 0

All variants with conflicting interpretations #

Total variants: 24
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_012301.4(MAGI2):c.3357A>G (p.Leu1119=) rs2074641 0.86492
NM_012301.4(MAGI2):c.3213G>A (p.Ser1071=) rs7812015 0.86488
NM_012301.4(MAGI2):c.1014G>A (p.Lys338=) rs3735442 0.33029
NM_012301.4(MAGI2):c.2784T>C (p.Asn928=) rs1009524 0.11193
NM_012301.4(MAGI2):c.3915G>A (p.Gln1305=) rs117054456 0.02550
NM_012301.4(MAGI2):c.2379C>T (p.Leu793=) rs73703715 0.00966
NM_012301.4(MAGI2):c.2329T>C (p.Leu777=) rs76346657 0.00722
NM_012301.4(MAGI2):c.276C>G (p.Pro92=) rs146012909 0.00597
NM_012301.4(MAGI2):c.900A>G (p.Glu300=) rs111635934 0.00217
NM_012301.4(MAGI2):c.2142G>A (p.Pro714=) rs144574076 0.00156
NM_012301.4(MAGI2):c.2213G>A (p.Arg738Gln) rs145722885 0.00153
NM_012301.4(MAGI2):c.219C>T (p.Pro73=) rs148240352 0.00143
NM_012301.4(MAGI2):c.2454C>T (p.Arg818=) rs148580718 0.00081
NM_012301.4(MAGI2):c.3706+5G>A rs188293910 0.00060
NM_012301.4(MAGI2):c.2616C>T (p.Asn872=) rs148005928 0.00051
NM_012301.4(MAGI2):c.3765C>T (p.Gly1255=) rs187773786 0.00039
NM_012301.4(MAGI2):c.2131C>A (p.Pro711Thr) rs144078604 0.00031
NM_012301.4(MAGI2):c.411G>A (p.Thr137=) rs149568072 0.00024
NM_012301.4(MAGI2):c.1737C>T (p.Asp579=) rs142555732 0.00009
NM_012301.4(MAGI2):c.1713C>T (p.Ser571=) rs587780386 0.00003
NM_012301.4(MAGI2):c.878C>T (p.Thr293Ile) rs587780389 0.00002
NM_012301.4(MAGI2):c.1425T>C (p.Tyr475=) rs148086431 0.00001
NM_012301.4(MAGI2):c.302-9dup
NM_012301.4(MAGI2):c.3786C>G (p.Leu1262=)

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