ClinVar Miner

Variants in gene MAGI2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
66 9 0 10 7 0 0 16

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 6 2
likely benign 6 0 10
benign 2 10 0

All variants with conflicting interpretations #

Total variants: 16
Download table as spreadsheet
HGVS dbSNP
NM_012301.4(MAGI2):c.1014G>A (p.Lys338=) rs3735442
NM_012301.4(MAGI2):c.1425T>C (p.Tyr475=) rs148086431
NM_012301.4(MAGI2):c.1713C>T (p.Ser571=) rs587780386
NM_012301.4(MAGI2):c.2131C>A (p.Pro711Thr) rs144078604
NM_012301.4(MAGI2):c.2142G>A (p.Pro714=) rs144574076
NM_012301.4(MAGI2):c.219C>T (p.Pro73=) rs148240352
NM_012301.4(MAGI2):c.2213G>A (p.Arg738Gln) rs145722885
NM_012301.4(MAGI2):c.2329T>C (p.Leu777=) rs76346657
NM_012301.4(MAGI2):c.2379C>T (p.Leu793=) rs73703715
NM_012301.4(MAGI2):c.2454C>T (p.Arg818=) rs148580718
NM_012301.4(MAGI2):c.276C>G (p.Pro92=) rs146012909
NM_012301.4(MAGI2):c.2784T>C (p.Asn928=) rs1009524
NM_012301.4(MAGI2):c.3213G>A (p.Ser1071=) rs7812015
NM_012301.4(MAGI2):c.3357A>G (p.Leu1119=) rs2074641
NM_012301.4(MAGI2):c.878C>T (p.Thr293Ile) rs587780389
NM_012301.4(MAGI2):c.900A>G (p.Glu300=) rs111635934

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