Variants in gene MCCC2 with conflicting interpretations "likely pathogenic" and "uncertain significance"

Submission 1 (likely pathogenic) minimum review status:		Submission 1 (likely pathogenic) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 18

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HGVS	dbSNP	gnomAD frequency
NM_022132.5(MCCC2):c.1433C>G (p.Ala478Gly)	rs35068278	0.00082
NM_022132.5(MCCC2):c.641G>C (p.Gly214Ala)	rs277995	0.00005
NM_022132.5(MCCC2):c.1309A>G (p.Ile437Val)	rs119103224	0.00004
NM_022132.5(MCCC2):c.653C>T (p.Ala218Val)	rs760420191	0.00003
NM_022132.5(MCCC2):c.129+3A>G	rs1352606118	0.00002
NM_022132.5(MCCC2):c.568C>T (p.His190Tyr)	rs773774134	0.00002
NM_022132.5(MCCC2):c.1342G>A (p.Gly448Arg)	rs766045910	0.00001
NM_022132.5(MCCC2):c.1441G>A (p.Val481Met)	rs767575019	0.00001
NM_022132.5(MCCC2):c.1488G>C (p.Gln496His)	rs745367639	0.00001
NM_022132.5(MCCC2):c.302C>T (p.Ser101Phe)	rs748028684	0.00001
NM_022132.5(MCCC2):c.499T>C (p.Cys167Arg)	rs119103222	0.00001
NM_022132.5(MCCC2):c.578G>A (p.Arg193His)	rs535519604	0.00001
NM_022132.5(MCCC2):c.1567A>G (p.Ser523Gly)	rs1459143051
NM_022132.5(MCCC2):c.1570G>A (p.Ala524Thr)
NM_022132.5(MCCC2):c.1635dup (p.Ser546Ter)	rs768272570
NM_022132.5(MCCC2):c.351_353del (p.Gly118del)	rs758794885
NM_022132.5(MCCC2):c.557_560delinsTTGTCGAGGTAAGTGT (p.Pro186_Asp187delinsLeuValGluValSerVal)	rs797044772
NM_022132.5(MCCC2):c.955G>A (p.Gly319Arg)	rs1443551700

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