Variants in gene MECP2 with conflicting interpretations "uncertain significance" and "likely pathogenic"

Submission 1 (uncertain significance) minimum review status:		Submission 1 (uncertain significance) method:
Submission 2 (likely pathogenic) minimum review status:		Submission 2 (likely pathogenic) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 20

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HGVS	dbSNP	gnomAD frequency
NM_001110792.2(MECP2):c.289C>T (p.Arg97Cys)	rs1064797047	0.00001
NM_001110792.2(MECP2):c.1000C>G (p.Pro334Ala)	rs61751449
NM_001110792.2(MECP2):c.1042C>G (p.Leu348Val)	rs587783104
NM_001110792.2(MECP2):c.1497A>C (p.Ter499Cys)	rs267608642
NM_001110792.2(MECP2):c.325G>T (p.Asp109Tyr)	rs61754448
NM_001110792.2(MECP2):c.337C>T (p.Pro113Ser)	rs61754452
NM_001110792.2(MECP2):c.379C>T (p.Arg127Cys)	rs267608388
NM_001110792.2(MECP2):c.419A>C (p.Gln140Pro)	rs61748383
NM_001110792.2(MECP2):c.428C>A (p.Ala143Asp)	rs267608470
NM_001110792.2(MECP2):c.433C>G (p.Arg145Gly)	rs28934904
NM_001110792.2(MECP2):c.488A>G (p.Asp163Gly)	rs61748403
NM_001110792.2(MECP2):c.503A>C (p.Asp168Ala)	rs61748407
NM_001110792.2(MECP2):c.503A>G (p.Asp168Gly)	rs61748407
NM_001110792.2(MECP2):c.505T>A (p.Phe169Ile)	rs61748410
NM_001110792.2(MECP2):c.517G>T (p.Gly173Trp)	rs61748416
NM_001110792.2(MECP2):c.518G>T (p.Gly173Val)	rs61748417
NM_001110792.2(MECP2):c.941C>T (p.Pro314Leu)	rs61749723
NM_001110792.2(MECP2):c.946A>G (p.Lys316Glu)	rs61751440
NM_001110792.2(MECP2):c.950A>G (p.Lys317Arg)	rs61751441
NM_001110792.2(MECP2):c.961C>T (p.Arg321Trp)	rs61751444

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