ClinVar Miner

Variants in gene MEN1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
526 169 3 35 18 0 7 56

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 17 2 0 0
likely pathogenic 17 0 6 0 0
uncertain significance 2 6 1 13 9
likely benign 0 0 13 0 18
benign 0 0 9 18 2

All variants with conflicting interpretations #

Total variants: 56
Download table as spreadsheet
HGVS dbSNP
NM_000244.3(MEN1):c.1018C>A (p.Arg340=) rs371364206
NM_000244.3(MEN1):c.1269C>T (p.Asp423=) rs2071313
NM_000244.3(MEN1):c.1A>G (p.Met1Val) rs386134250
NM_000244.3(MEN1):c.526C>T (p.Arg176Trp) rs143329068
NM_000244.3(MEN1):c.669+18C>T rs180737290
NM_000244.3(MEN1):c.670-5dupC rs772016629
NM_130799.2(MEN1):c.*470A>G rs778272737
NM_130799.2(MEN1):c.-20G>A rs386134244
NM_130799.2(MEN1):c.-22C>A rs374749001
NM_130799.2(MEN1):c.-35A>C rs679946
NM_130799.2(MEN1):c.-35A>T rs679946
NM_130799.2(MEN1):c.1049+1G>C rs1114167489
NM_130799.2(MEN1):c.1049+9C>T rs200517349
NM_130799.2(MEN1):c.1075_1077delGAG (p.Glu359del) rs1060499971
NM_130799.2(MEN1):c.1170G>A (p.Pro390=) rs587780841
NM_130799.2(MEN1):c.1174delG (p.Glu392Serfs) rs386134247
NM_130799.2(MEN1):c.1296G>A (p.Leu432=) rs138770431
NM_130799.2(MEN1):c.1308G>T (p.Trp436Cys) rs398124435
NM_130799.2(MEN1):c.133G>A (p.Glu45Lys) rs1114167491
NM_130799.2(MEN1):c.1351-4C>T rs764408631
NM_130799.2(MEN1):c.1409C>T (p.Pro470Leu) rs750112288
NM_130799.2(MEN1):c.1416C>T (p.Gly472=) rs764509990
NM_130799.2(MEN1):c.1434C>T (p.Gly478=) rs200280309
NM_130799.2(MEN1):c.1508G>A (p.Gly503Asp) rs375804228
NM_130799.2(MEN1):c.1579C>T (p.Arg527Ter) rs104894261
NM_130799.2(MEN1):c.1609G>A (p.Val537Met) rs1057521847
NM_130799.2(MEN1):c.1621G>A (p.Ala541Thr) rs2959656
NM_130799.2(MEN1):c.1638G>A (p.Pro546=) rs368783097
NM_130799.2(MEN1):c.1660C>T (p.Gln554Ter) rs794728631
NM_130799.2(MEN1):c.1664G>A (p.Ser555Asn) rs863224527
NM_130799.2(MEN1):c.168delC (p.Asn57Thrfs) rs1060499990
NM_130799.2(MEN1):c.1764G>A (p.Lys588=) rs373669288
NM_130799.2(MEN1):c.1A>T (p.Met1Leu) rs386134250
NM_130799.2(MEN1):c.266_286del21 (p.Leu89_Ala95del) rs1064792906
NM_130799.2(MEN1):c.30G>T (p.Leu10=) rs371192390
NM_130799.2(MEN1):c.3G>A (p.Met1Ile) rs786204242
NM_130799.2(MEN1):c.435C>T (p.Ser145=) rs61736636
NM_130799.2(MEN1):c.467G>A (p.Gly156Asp) rs794728648
NM_130799.2(MEN1):c.512G>A (p.Arg171Gln) rs607969
NM_130799.2(MEN1):c.514G>T (p.Asp172Tyr) rs1114167494
NM_130799.2(MEN1):c.597C>T (p.His199=) rs150512958
NM_130799.2(MEN1):c.655-4delT rs748005956
NM_130799.2(MEN1):c.655-6C>A rs77461664
NM_130799.2(MEN1):c.655-6C>G rs77461664
NM_130799.2(MEN1):c.655-6C>T rs77461664
NM_130799.2(MEN1):c.65T>G (p.Leu22Arg) rs104894256
NM_130799.2(MEN1):c.668T>C (p.Leu223Pro) rs886039415
NM_130799.2(MEN1):c.722G>A (p.Cys241Tyr) rs794728624
NM_130799.2(MEN1):c.76G>A (p.Glu26Lys) rs28931612
NM_130799.2(MEN1):c.774G>C (p.Gln258His) rs374659656
NM_130799.2(MEN1):c.783+1G>A rs794728652
NM_130799.2(MEN1):c.784-15_784-14delTC rs764290037
NM_130799.2(MEN1):c.825-10C>G rs999121619
NM_130799.2(MEN1):c.830C>A (p.Pro277His) rs1060499973
NM_130799.2(MEN1):c.912+1G>C rs398124437
NM_130799.2(MEN1):c.913-2A>G rs1114167498

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.