ClinVar Miner

Variants in gene MESP2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
62 6 4 7 2 0 0 13

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 4 1 0 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 0 0 0 1 1
likely benign 0 0 1 0 6
benign 0 0 1 6 0

All variants with conflicting interpretations #

Total variants: 13
Download table as spreadsheet
HGVS dbSNP
NM_001039958.1(MESP2):c.547_582del36 (p.Gln194_Gly205del) rs749710849
NM_001039958.1(MESP2):c.558_569delGGGGCAGGGGCA (p.Gln202_Gly205del) rs56192595
NM_001039958.2(MESP2):c.197C>G (p.Ala66Gly) rs71647809
NM_001039958.2(MESP2):c.241G>T (p.Gly81Ter) rs118204034
NM_001039958.2(MESP2):c.306C>A (p.His102Gln) rs77473319
NM_001039958.2(MESP2):c.307G>T (p.Glu103Ter) rs71647808
NM_001039958.2(MESP2):c.373C>G (p.Leu125Val) rs71647806
NM_001039958.2(MESP2):c.500_503dup (p.Gly169Profs) rs113994158
NM_001039958.2(MESP2):c.531G>A (p.Ala177=) rs75049807
NM_001039958.2(MESP2):c.558G>A (p.Gln186=) rs28546919
NM_001039958.2(MESP2):c.573G>A (p.Gly191=) rs113097169
NM_001039958.2(MESP2):c.671C>T (p.Ser224Phe) rs71647807
NM_001039958.2(MESP2):c.700G>T (p.Glu234Ter) rs118204035

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