Variants in gene MTHFR with conflicting interpretations "benign" and "likely benign"

Submission 1 (benign) minimum review status:		Submission 1 (benign) method:
Submission 2 (likely benign) minimum review status:		Submission 2 (likely benign) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 15

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HGVS	dbSNP	gnomAD frequency
NM_005957.5(MTHFR):c.1286A>C (p.Glu429Ala)	rs1801131	0.25830
NM_005957.5(MTHFR):c.1781G>A (p.Arg594Gln)	rs2274976	0.03996
NM_005957.5(MTHFR):c.1958C>T (p.Thr653Met)	rs35737219	0.01462
NM_005957.5(MTHFR):c.1476G>A (p.Pro492=)	rs35653697	0.00937
NM_005957.5(MTHFR):c.1264G>A (p.Gly422Arg)	rs45571736	0.00300
NM_005957.5(MTHFR):c.236+3A>G	rs1413355	0.00233
NM_005957.5(MTHFR):c.348C>T (p.Ala116=)	rs144921426	0.00217
NM_005957.5(MTHFR):c.1959G>A (p.Thr653=)	rs45572531	0.00187
NM_005957.5(MTHFR):c.1761C>T (p.Ala587=)	rs115049252	0.00145
NM_005957.5(MTHFR):c.708C>T (p.Phe236=)	rs34279942	0.00134
NM_005957.5(MTHFR):c.1556G>T (p.Arg519Leu)	rs45449298	0.00118
NM_005957.5(MTHFR):c.732C>T (p.Thr244=)	rs45486194	0.00082
NM_005957.5(MTHFR):c.870C>T (p.Asn290=)	rs141769179	0.00019
NM_005957.5(MTHFR):c.726A>G (p.Ala242=)	rs45459991	0.00011
NM_005957.5(MTHFR):c.1626T>C (p.Asn542=)	rs190046545	0.00005

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