ClinVar Miner

Variants in gene MYH6 with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
665 96 0 57 52 0 3 101

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 0 2 1 0
likely pathogenic 0 0 1 0 0
uncertain significance 2 1 0 45 15
likely benign 1 0 45 0 57
benign 0 0 15 57 0

All variants with conflicting interpretations #

Total variants: 101
Download table as spreadsheet
HGVS dbSNP
NM_002471.3(MYH6):c.1944G>A (p.Thr648=) rs367742240
NM_002471.3(MYH6):c.2384G>A (p.Arg795Gln) rs267606907
NM_002471.3(MYH6):c.2430-4C>A rs376527296
NM_002471.3(MYH6):c.2520G>A (p.Pro840=) rs141945051
NM_002471.3(MYH6):c.2685+14A>T rs765118655
NM_002471.3(MYH6):c.3343-3del rs1027186100
NM_002471.3(MYH6):c.3979-10C>A rs28730768
NM_002471.3(MYH6):c.3979-11C>G rs200618133
NM_002471.3(MYH6):c.3979-14C>A rs372226248
NM_002471.3(MYH6):c.3979-7del rs397516766
NM_002471.3(MYH6):c.3979-8C>T rs555976716
NM_002471.3(MYH6):c.3979-8del rs193922652
NM_002471.3(MYH6):c.4026C>A (p.Cys1342Ter) rs141062252
NM_002471.3(MYH6):c.4695A>G (p.Leu1565=) rs374702183
NM_002471.3(MYH6):c.4812T>C (p.Asp1604=) rs201667127
NM_002471.3(MYH6):c.5367G>A (p.Glu1789=) rs753335327
NM_002471.3(MYH6):c.5403G>A (p.Glu1801=) rs762151922
NM_002471.3(MYH6):c.5410C>A (p.Gln1804Lys) rs144571463
NM_002471.3(MYH6):c.5566-7C>T rs200509899
NM_002471.3(MYH6):c.5598A>G (p.Leu1866=) rs17091278
NM_002471.3(MYH6):c.5652C>T (p.Ala1884=) rs200662317
NM_002471.4(MYH6):c.*8T>C rs201560522
NM_002471.4(MYH6):c.1071C>T (p.Ile357=) rs58131640
NM_002471.4(MYH6):c.1108C>T (p.Arg370Trp) rs753444140
NM_002471.4(MYH6):c.1122G>A (p.Ala374=) rs148091079
NM_002471.4(MYH6):c.1131C>G (p.Asp377Glu) rs61742472
NM_002471.4(MYH6):c.1131C>T (p.Asp377=) rs61742472
NM_002471.4(MYH6):c.1252G>A (p.Val418Met) rs147606900
NM_002471.4(MYH6):c.1275C>T (p.Ile425=) rs61742470
NM_002471.4(MYH6):c.1335C>T (p.Asn445=) rs61731179
NM_002471.4(MYH6):c.1410C>T (p.Asp470=) rs139886074
NM_002471.4(MYH6):c.1582-7C>T rs374941865
NM_002471.4(MYH6):c.1763A>C (p.Asp588Ala) rs142992009
NM_002471.4(MYH6):c.1779C>A (p.Gly593=) rs190996339
NM_002471.4(MYH6):c.1809C>T (p.Asn603=) rs186134696
NM_002471.4(MYH6):c.1989C>T (p.Asn663=) rs28730774
NM_002471.4(MYH6):c.2071G>A (p.Val691Ile) rs148915045
NM_002471.4(MYH6):c.2097C>T (p.Gly699=) rs149734381
NM_002471.4(MYH6):c.2151C>T (p.Tyr717=) rs76202964
NM_002471.4(MYH6):c.2401A>G (p.Ile801Val) rs75487328
NM_002471.4(MYH6):c.2430-14C>T rs190342289
NM_002471.4(MYH6):c.2579G>A (p.Arg860His) rs115845031
NM_002471.4(MYH6):c.2806G>T (p.Ala936Ser) rs141704264
NM_002471.4(MYH6):c.2890G>T (p.Ala964Ser) rs144907522
NM_002471.4(MYH6):c.2928+5G>A rs28730772
NM_002471.4(MYH6):c.2946G>A (p.Glu982=) rs145274612
NM_002471.4(MYH6):c.3010G>T (p.Ala1004Ser) rs143978652
NM_002471.4(MYH6):c.3195G>C (p.Gln1065His) rs267606904
NM_002471.4(MYH6):c.3199A>G (p.Ser1067Gly) rs145508517
NM_002471.4(MYH6):c.3297G>A (p.Glu1099=) rs144957142
NM_002471.4(MYH6):c.3302T>C (p.Val1101Ala) rs365990
NM_002471.4(MYH6):c.3388G>A (p.Ala1130Thr) rs28730771
NM_002471.4(MYH6):c.3408G>A (p.Lys1136=) rs28730770
NM_002471.4(MYH6):c.3480C>T (p.Ser1160=) rs373345984
NM_002471.4(MYH6):c.3609C>G (p.Ala1203=) rs149369904
NM_002471.4(MYH6):c.3627C>T (p.Ile1209=) rs147871745
NM_002471.4(MYH6):c.3860-15T>G rs200883903
NM_002471.4(MYH6):c.3883G>C (p.Glu1295Gln) rs34935550
NM_002471.4(MYH6):c.3927T>C (p.Ser1309=) rs115742584
NM_002471.4(MYH6):c.3978+8C>T rs367866050
NM_002471.4(MYH6):c.3979-8_3979-7delinsGC rs727503235
NM_002471.4(MYH6):c.4011G>A (p.Ser1337=) rs451794
NM_002471.4(MYH6):c.4136C>T (p.Thr1379Met) rs145611185
NM_002471.4(MYH6):c.4206C>T (p.Ala1402=) rs111638554
NM_002471.4(MYH6):c.4293G>A (p.Met1431Ile) rs201016285
NM_002471.4(MYH6):c.4320T>A (p.Ala1440=) rs145566711
NM_002471.4(MYH6):c.4359+13C>T rs8022522
NM_002471.4(MYH6):c.4359+5A>G rs193283041
NM_002471.4(MYH6):c.4359+8A>C rs188675676
NM_002471.4(MYH6):c.4360-7C>T rs58949384
NM_002471.4(MYH6):c.4401T>G (p.Ser1467=) rs150081280
NM_002471.4(MYH6):c.4416A>G (p.Ser1472=) rs140800076
NM_002471.4(MYH6):c.4527G>A (p.Glu1509=) rs34855944
NM_002471.4(MYH6):c.4536G>A (p.Ser1512=) rs142539180
NM_002471.4(MYH6):c.4595G>T (p.Arg1532Leu) rs34330111
NM_002471.4(MYH6):c.4651-12A>C rs193922653
NM_002471.4(MYH6):c.4778A>T (p.Gln1593Leu) rs45574136
NM_002471.4(MYH6):c.4782G>A (p.Arg1594=) rs142823394
NM_002471.4(MYH6):c.4838T>C (p.Val1613Ala) rs61742476
NM_002471.4(MYH6):c.4905C>T (p.Asn1635=) rs143048583
NM_002471.4(MYH6):c.4906C>T (p.Arg1636Cys) rs149460065
NM_002471.4(MYH6):c.4914T>C (p.Ala1638=) rs178640
NM_002471.4(MYH6):c.4959+12C>T rs371661383
NM_002471.4(MYH6):c.4959+13G>A rs28730765
NM_002471.4(MYH6):c.4960-9G>A rs557113705
NM_002471.4(MYH6):c.4980C>T (p.Asp1660=) rs382872
NM_002471.4(MYH6):c.4986G>A (p.Ala1662=) rs77416370
NM_002471.4(MYH6):c.5112G>A (p.Ala1704=) rs150450178
NM_002471.4(MYH6):c.5259C>T (p.Ala1753=) rs8004990
NM_002471.4(MYH6):c.5400C>T (p.Asp1800=) rs144329079
NM_002471.4(MYH6):c.5439G>A (p.Gln1813=) rs200854143
NM_002471.4(MYH6):c.5475G>A (p.Glu1825=) rs79143968
NM_002471.4(MYH6):c.5662-6C>T rs183733802
NM_002471.4(MYH6):c.643-5C>T rs199859986
NM_002471.4(MYH6):c.679G>A (p.Ala227Thr) rs201828188
NM_002471.4(MYH6):c.800-11A>G rs434273
NM_002471.4(MYH6):c.824T>A (p.Ile275Asn) rs201327273
NM_002471.4(MYH6):c.831G>T (p.Gln277His) rs140660481
NM_002471.4(MYH6):c.909G>A (p.Leu303=) rs17091623
NM_002471.4(MYH6):c.981C>T (p.Ser327=) rs148407931
NM_002471.4(MYH6):c.999C>T (p.Thr333=) rs78107039

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