ClinVar Miner

Variants in gene combination MYH8, MYHAS with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
116 9 0 22 10 0 0 28

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

uncertain significance likely benign benign
uncertain significance 0 6 8
likely benign 6 0 22
benign 8 22 0

All variants with conflicting interpretations #

Total variants: 28
Download table as spreadsheet
HGVS dbSNP
NM_002472.3(MYH8):c.1209C>A (p.Cys403Ter) rs144321381
NM_002472.3(MYH8):c.1701G>A (p.Gln567=) rs73275411
NM_002472.3(MYH8):c.1731G>C (p.Glu577Asp) rs75160168
NM_002472.3(MYH8):c.1907C>T (p.Ala636Val) rs34693726
NM_002472.3(MYH8):c.2016C>T (p.Phe672=) rs12936716
NM_002472.3(MYH8):c.2147T>A (p.Ile716Asn) rs115483891
NM_002472.3(MYH8):c.225G>C (p.Arg75Ser) rs146732664
NM_002472.3(MYH8):c.2274A>G (p.Gln758=) rs145901155
NM_002472.3(MYH8):c.2432+6A>C rs111692916
NM_002472.3(MYH8):c.3117G>A (p.Gly1039=) rs3744553
NM_002472.3(MYH8):c.3254+1G>T rs372740784
NM_002472.3(MYH8):c.3270C>T (p.Ile1090=) rs3744552
NM_002472.3(MYH8):c.3340T>C (p.Leu1114=) rs142711931
NM_002472.3(MYH8):c.3686T>C (p.Met1229Thr) rs35962914
NM_002472.3(MYH8):c.4233C>T (p.Asn1411=) rs138992963
NM_002472.3(MYH8):c.4740A>C (p.Ala1580=) rs61730806
NM_002472.3(MYH8):c.5074T>C (p.Trp1692Arg) rs8069834
NM_002472.3(MYH8):c.5208C>T (p.Asp1736=) rs33969260
NM_002472.3(MYH8):c.5293-1G>A rs144785726
NM_002472.3(MYH8):c.5350C>G (p.Arg1784Gly) rs141215006
NM_002472.3(MYH8):c.540C>T (p.Thr180=) rs34613390
NM_002472.3(MYH8):c.5464G>A (p.Val1822Ile) rs143876651
NM_002472.3(MYH8):c.5513A>C (p.Glu1838Ala) rs111567318
NM_002472.3(MYH8):c.5539G>A (p.Glu1847Lys) rs757938047
NM_002472.3(MYH8):c.578G>A (p.Arg193His) rs145863180
NM_002472.3(MYH8):c.675C>T (p.Ser225=) rs146651214
NM_002472.3(MYH8):c.714T>C (p.Thr238=) rs8068729
NM_002472.3(MYH8):c.805+9C>T rs75468422

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