Variants in gene NLRP3 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status:		Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 15

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HGVS	dbSNP	gnomAD frequency
NM_001243133.2(NLRP3):c.2107C>A (p.Gln703Lys)	rs35829419	0.03262
NM_001243133.2(NLRP3):c.592G>A (p.Val198Met)	rs121908147	0.00835
NM_001243133.2(NLRP3):c.3048A>C (p.Leu1016Phe)	rs143548979	0.00068
NM_001243133.2(NLRP3):c.1639A>T (p.Ser547Cys)	rs139833874	0.00061
NM_001243133.2(NLRP3):c.2855C>T (p.Thr952Met)	rs139814109	0.00051
NM_001243133.2(NLRP3):c.2176A>G (p.Ser726Gly)	rs147946775	0.00049
NM_001243133.2(NLRP3):c.208G>A (p.Val70Met)	rs117287351	0.00031
NM_001243133.2(NLRP3):c.404G>A (p.Arg135His)	rs138946894	0.00029
NM_001243133.2(NLRP3):c.674C>T (p.Ala225Val)	rs180177493	0.00019
NM_001243133.2(NLRP3):c.944C>T (p.Pro315Leu)	rs180177462	0.00010
NM_001243133.2(NLRP3):c.1361G>A (p.Gly454Glu)	rs199696688	0.00006
NM_001243133.2(NLRP3):c.2761A>G (p.Thr921Ala)	rs200089542	0.00004
NM_001243133.2(NLRP3):c.2419G>A (p.Ala807Thr)	rs201096167	0.00002
NM_001243133.2(NLRP3):c.2732A>G (p.Asn911Ser)	rs577683668	0.00002
NM_001243133.2(NLRP3):c.224C>T (p.Ala75Val)	rs200288250

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