ClinVar Miner

Variants in gene NTRK1 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status: Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 74
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HGVS dbSNP gnomAD frequency
NM_002529.4(NTRK1):c.2339G>A (p.Arg780Gln) rs35669708 0.00406
NM_002529.4(NTRK1):c.157G>C (p.Asp53His) rs200815412 0.00187
NM_002529.4(NTRK1):c.865C>A (p.Gln289Lys) rs137979116 0.00118
NM_002529.4(NTRK1):c.602C>A (p.Pro201His) rs146201511 0.00061
NM_002529.4(NTRK1):c.1320C>G (p.Asn440Lys) rs147443162 0.00050
NM_002529.4(NTRK1):c.1803C>G (p.Leu601=) rs146129485 0.00042
NM_002529.4(NTRK1):c.1474G>A (p.Glu492Lys) rs144901788 0.00040
NM_002529.4(NTRK1):c.*6C>T rs370807813 0.00037
NM_002529.4(NTRK1):c.482G>A (p.Arg161His) rs150271893 0.00031
NM_002529.4(NTRK1):c.1068C>T (p.Asn356=) rs145823996 0.00029
NM_002529.4(NTRK1):c.575G>C (p.Gly192Ala) rs201185829 0.00027
NM_002529.4(NTRK1):c.641G>A (p.Arg214Gln) rs200132482 0.00023
NM_002529.4(NTRK1):c.630C>T (p.Asp210=) rs147882947 0.00021
NM_002529.4(NTRK1):c.504C>T (p.Gly168=) rs144594313 0.00018
NM_002529.4(NTRK1):c.631G>A (p.Val211Met) rs201192875 0.00017
NM_002529.4(NTRK1):c.584C>T (p.Thr195Met) rs552776147 0.00014
NM_002529.4(NTRK1):c.1661G>A (p.Arg554Gln) rs764417252 0.00013
NM_002529.4(NTRK1):c.570C>G (p.Ser190Arg) rs138608619 0.00013
NM_002529.4(NTRK1):c.1808C>G (p.Ser603Cys) rs188270548 0.00011
NM_002529.4(NTRK1):c.279G>A (p.Leu93=) rs147983523 0.00011
NM_002529.4(NTRK1):c.711G>A (p.Thr237=) rs537430475 0.00010
NM_002529.4(NTRK1):c.659G>A (p.Arg220Gln) rs540751200 0.00009
NM_002529.4(NTRK1):c.509T>C (p.Val170Ala) rs201503610 0.00008
NM_002529.4(NTRK1):c.824A>C (p.Glu275Ala) rs138533001 0.00008
NM_002529.4(NTRK1):c.585G>A (p.Thr195=) rs182531655 0.00007
NM_002529.4(NTRK1):c.658C>T (p.Arg220Trp) rs202030811 0.00007
NM_002529.4(NTRK1):c.1522C>A (p.Arg508=) rs200575096 0.00006
NM_002529.4(NTRK1):c.2113A>T (p.Thr705Ser) rs200935209 0.00006
NM_002529.4(NTRK1):c.2231G>A (p.Arg744His) rs751281792 0.00006
NM_002529.4(NTRK1):c.470G>A (p.Arg157His) rs141021604 0.00006
NM_002529.4(NTRK1):c.575-15G>A rs762788551 0.00006
NM_002529.4(NTRK1):c.850+11G>A rs372293237 0.00006
NM_002529.4(NTRK1):c.1939G>T (p.Val647Leu) rs142870382 0.00005
NM_002529.4(NTRK1):c.357C>T (p.Arg119=) rs149960336 0.00005
NM_002529.4(NTRK1):c.375C>T (p.Asn125=) rs757803799 0.00005
NM_002529.4(NTRK1):c.1252-6C>G rs776728101 0.00004
NM_002529.4(NTRK1):c.1796G>A (p.Arg599His) rs775718859 0.00004
NM_002529.4(NTRK1):c.288-5C>T rs200860423 0.00004
NM_002529.4(NTRK1):c.818G>A (p.Arg273Gln) rs200305545 0.00004
NM_002529.4(NTRK1):c.1473C>T (p.Ile491=) rs373181158 0.00003
NM_002529.4(NTRK1):c.1778G>A (p.Arg593Gln) rs748133401 0.00003
NM_002529.4(NTRK1):c.219C>T (p.Ile73=) rs563296138 0.00003
NM_002529.4(NTRK1):c.2338C>T (p.Arg780Trp) rs537948663 0.00003
NM_002529.4(NTRK1):c.2355C>T (p.Ala785=) rs772156529 0.00003
NM_002529.4(NTRK1):c.676G>A (p.Gly226Ser) rs760918699 0.00003
NM_002529.4(NTRK1):c.808G>A (p.Asp270Asn) rs145222195 0.00003
NM_002529.4(NTRK1):c.954T>C (p.Asn318=) rs769539870 0.00003
NM_002529.4(NTRK1):c.1237G>C (p.Glu413Gln) rs199826686 0.00002
NM_002529.4(NTRK1):c.1805+8C>A rs780424308 0.00002
NM_002529.4(NTRK1):c.1917G>A (p.Val639=) rs760171782 0.00002
NM_002529.4(NTRK1):c.2047-8C>T rs769308621 0.00002
NM_002529.4(NTRK1):c.2169C>T (p.Tyr723=) rs140852621 0.00002
NM_002529.4(NTRK1):c.2205+10G>A rs368713268 0.00002
NM_002529.4(NTRK1):c.65T>A (p.Leu22Gln) rs748402400 0.00002
NM_002529.4(NTRK1):c.1005G>A (p.Pro335=) rs780334454 0.00001
NM_002529.4(NTRK1):c.1196-11T>C rs1024148691 0.00001
NM_002529.4(NTRK1):c.1359G>A (p.Pro453=) rs200937156 0.00001
NM_002529.4(NTRK1):c.1646C>T (p.Ala549Val) rs763247367 0.00001
NM_002529.4(NTRK1):c.1647G>A (p.Ala549=) rs771010259 0.00001
NM_002529.4(NTRK1):c.1650C>T (p.Ser550=) rs774664479 0.00001
NM_002529.4(NTRK1):c.1734C>G (p.Val578=) rs953974597 0.00001
NM_002529.4(NTRK1):c.2047-6T>C rs762866535 0.00001
NM_002529.4(NTRK1):c.2124C>T (p.Ser708=) rs1371693296 0.00001
NM_002529.4(NTRK1):c.311G>A (p.Arg104His) rs578095133 0.00001
NM_002529.4(NTRK1):c.326A>G (p.Asp109Gly) rs141592864 0.00001
NM_002529.4(NTRK1):c.1196-9T>C rs760602338
NM_002529.4(NTRK1):c.1521C>T (p.Arg507=) rs901135479
NM_002529.4(NTRK1):c.1569G>A (p.Lys523=) rs1647889781
NM_002529.4(NTRK1):c.213-5C>G rs757323460
NM_002529.4(NTRK1):c.2205+13C>A rs1648175536
NM_002529.4(NTRK1):c.2214C>T (p.Asp738=) rs1648253157
NM_002529.4(NTRK1):c.2301G>A (p.Glu767=) rs753397054
NM_002529.4(NTRK1):c.435G>C (p.Leu145=) rs1647275742
NM_002529.4(NTRK1):c.468G>C (p.Leu156=) rs991397214

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