ClinVar Miner

Variants in gene POLD1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
947 433 0 71 75 3 0 139

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor
pathogenic 0 2 0 0 0 2
likely pathogenic 2 0 0 0 0 2
uncertain significance 0 0 0 74 9 1
likely benign 0 0 74 0 69 0
benign 0 0 9 69 0 0
risk factor 2 2 1 0 0 0

All variants with conflicting interpretations #

Total variants: 139
Download table as spreadsheet
HGVS dbSNP
NM_001256849.1(POLD1):c.1421T>C (p.Leu474Pro) rs587777627
NM_001256849.1(POLD1):c.1433G>A (p.Ser478Asn) rs397514632
NM_001256849.1(POLD1):c.17G>A (p.Arg6Gln) rs778275831
NM_001256849.1(POLD1):c.2007-4G>A rs202035484
NM_001256849.1(POLD1):c.2275G>A (p.Val759Ile) rs145473716
NM_001256849.1(POLD1):c.3218+10A>G rs2463239
NM_001256849.1(POLD1):c.463+8G>T rs1726802
NM_001256849.1(POLD1):c.56G>A (p.Arg19His) rs3218773
NM_001256849.1(POLD1):c.980C>T (p.Pro327Leu) rs397514633
NM_002691.3(POLD1):c.1017G>T (p.Ser339=) rs373404887
NM_002691.3(POLD1):c.1061C>T (p.Ala354Val) rs140990974
NM_002691.3(POLD1):c.1092G>C (p.Leu364=) rs139883454
NM_002691.3(POLD1):c.1118A>G (p.Lys373Arg) rs770407151
NM_002691.3(POLD1):c.1138-3C>T rs200072694
NM_002691.3(POLD1):c.1138-8A>G rs41544624
NM_002691.3(POLD1):c.1148C>T (p.Thr383Ile) rs201654210
NM_002691.3(POLD1):c.1173C>T (p.Asp391=) rs2230244
NM_002691.3(POLD1):c.1275C>T (p.Ala425=) rs3219392
NM_002691.3(POLD1):c.1384-13C>G rs536467012
NM_002691.3(POLD1):c.13C>T (p.Arg5Trp) rs9282830
NM_002691.3(POLD1):c.1422C>T (p.Leu474=) rs369332787
NM_002691.3(POLD1):c.1449C>T (p.Gly483=) rs878854522
NM_002691.3(POLD1):c.1494+5C>T rs565428379
NM_002691.3(POLD1):c.1503C>T (p.Asn501=) rs371647100
NM_002691.3(POLD1):c.1504G>A (p.Asp502Asn) rs777866589
NM_002691.3(POLD1):c.1527T>A (p.Ala509=) rs1229053013
NM_002691.3(POLD1):c.1539G>A (p.Leu513=) rs2230246
NM_002691.3(POLD1):c.1548C>T (p.Ala516=) rs2230247
NM_002691.3(POLD1):c.1594G>A (p.Ala532Thr) rs765276497
NM_002691.3(POLD1):c.1608G>A (p.Ala536=) rs568549476
NM_002691.3(POLD1):c.1620C>T (p.Gly540=) rs140216790
NM_002691.3(POLD1):c.1665C>T (p.Val555=) rs150238541
NM_002691.3(POLD1):c.1687-5C>T rs199733325
NM_002691.3(POLD1):c.1713C>T (p.Pro571=) rs2230248
NM_002691.3(POLD1):c.1761C>T (p.Ile587=) rs3218755
NM_002691.3(POLD1):c.1795G>A (p.Ala599Thr) rs149569984
NM_002691.3(POLD1):c.1860G>A (p.Thr620=) rs1726790
NM_002691.3(POLD1):c.1869G>T (p.Arg623=) rs748380365
NM_002691.3(POLD1):c.1893-6A>C rs963949260
NM_002691.3(POLD1):c.1932C>G (p.Asp644Glu) rs80214209
NM_002691.3(POLD1):c.1932C>T (p.Asp644=) rs80214209
NM_002691.3(POLD1):c.1977C>T (p.Ile659=) rs45605236
NM_002691.3(POLD1):c.2007-5C>T rs199506387
NM_002691.3(POLD1):c.202+3A>G rs375365167
NM_002691.3(POLD1):c.2052G>C (p.Gln684His) rs144143245
NM_002691.3(POLD1):c.208G>A (p.Val70Ile) rs147911699
NM_002691.3(POLD1):c.2100A>G (p.Val700=) rs772468675
NM_002691.3(POLD1):c.2103C>T (p.Tyr701=) rs201483538
NM_002691.3(POLD1):c.2155-6C>T rs112481714
NM_002691.3(POLD1):c.2163G>A (p.Thr721=) rs763876339
NM_002691.3(POLD1):c.2178G>C (p.Gln726His) rs747483140
NM_002691.3(POLD1):c.2185G>A (p.Glu729Lys) rs200931999
NM_002691.3(POLD1):c.2250+4G>A rs370478977
NM_002691.3(POLD1):c.2250+7G>A rs775363857
NM_002691.3(POLD1):c.2251-4G>A rs768364989
NM_002691.3(POLD1):c.2251-5C>T rs1236954722
NM_002691.3(POLD1):c.2251-8G>A rs56051075
NM_002691.3(POLD1):c.2337G>A (p.Ala779=) rs147108748
NM_002691.3(POLD1):c.234C>G (p.Arg78=) rs2228665
NM_002691.3(POLD1):c.2388+4C>T rs371542643
NM_002691.3(POLD1):c.2388+9C>G rs1001555540
NM_002691.3(POLD1):c.2429C>T (p.Ala810Val) rs765981178
NM_002691.3(POLD1):c.2433C>T (p.Gly811=) rs1051057675
NM_002691.3(POLD1):c.2577C>T (p.Gly859=) rs149366027
NM_002691.3(POLD1):c.2599G>A (p.Val867Ile) rs367680864
NM_002691.3(POLD1):c.2628C>T (p.Ile876=) rs75874199
NM_002691.3(POLD1):c.2700C>T (p.His900=) rs769965495
NM_002691.3(POLD1):c.2717+11G>A rs753506843
NM_002691.3(POLD1):c.2717+9C>A rs760140187
NM_002691.3(POLD1):c.2718-4G>A rs755348897
NM_002691.3(POLD1):c.2718-5C>T rs368965066
NM_002691.3(POLD1):c.2757C>T (p.Gly919=) rs757406292
NM_002691.3(POLD1):c.2821-4G>A rs369042179
NM_002691.3(POLD1):c.2821-5C>T rs1057521374
NM_002691.3(POLD1):c.2829G>A (p.Leu943=) rs1225289450
NM_002691.3(POLD1):c.2832C>T (p.Phe944=) rs143974331
NM_002691.3(POLD1):c.2838G>A (p.Leu946=) rs1060501814
NM_002691.3(POLD1):c.2953+4C>T rs1057521166
NM_002691.3(POLD1):c.2955G>T (p.Arg985=) rs770495723
NM_002691.3(POLD1):c.2967G>A (p.Thr989=) rs3218752
NM_002691.3(POLD1):c.2979G>A (p.Thr993=) rs3218774
NM_002691.3(POLD1):c.2988G>A (p.Thr996=) rs542996664
NM_002691.3(POLD1):c.3054G>A (p.Val1018=) rs369613619
NM_002691.3(POLD1):c.3067+6C>T rs1057522005
NM_002691.3(POLD1):c.3068-5C>T rs759650325
NM_002691.3(POLD1):c.3120+6_3120+21del16 rs1064792944
NM_002691.3(POLD1):c.3121-8G>A rs762920108
NM_002691.3(POLD1):c.317-5C>T rs768082423
NM_002691.3(POLD1):c.3198C>T (p.His1066=) rs569987101
NM_002691.3(POLD1):c.3204C>T (p.Asp1068=) rs759019419
NM_002691.3(POLD1):c.3218+5G>A rs569395274
NM_002691.3(POLD1):c.3218+9_3218+10invCA
NM_002691.3(POLD1):c.3219-19C>A rs374168125
NM_002691.3(POLD1):c.3219-21_3219-10dupTGCCCCTGCCCC rs3219456
NM_002691.3(POLD1):c.3219-5C>T rs748304578
NM_002691.3(POLD1):c.3231C>T (p.Pro1077=) rs770660636
NM_002691.3(POLD1):c.324G>T (p.Ala108=) rs20582
NM_002691.3(POLD1):c.3258G>C (p.Arg1086=) rs776167760
NM_002691.3(POLD1):c.33C>T (p.Pro11=) rs3218768
NM_002691.3(POLD1):c.371T>C (p.Val124Ala) rs199993010
NM_002691.3(POLD1):c.378C>T (p.Arg126=) rs145324823
NM_002691.3(POLD1):c.399G>A (p.Glu133=) rs757940686
NM_002691.3(POLD1):c.433G>A (p.Ala145Thr) rs137953986
NM_002691.3(POLD1):c.455C>T (p.Ala152Val) rs41563714
NM_002691.3(POLD1):c.463+8_463+9delinsTT rs796285537
NM_002691.3(POLD1):c.495A>G (p.Gln165=) rs756717437
NM_002691.3(POLD1):c.518G>A (p.Ser173Asn) rs1726803
NM_002691.3(POLD1):c.534G>T (p.Gly178=) rs376129517
NM_002691.3(POLD1):c.55C>T (p.Arg19Cys) rs368033860
NM_002691.3(POLD1):c.581C>G (p.Ser194Cys) rs144656348
NM_002691.3(POLD1):c.583C>T (p.Arg195Ter) rs377690809
NM_002691.3(POLD1):c.589A>C (p.Ser197Arg) rs1040524947
NM_002691.3(POLD1):c.612C>T (p.His204=) rs147881471
NM_002691.3(POLD1):c.624G>A (p.Pro208=) rs78996304
NM_002691.3(POLD1):c.639C>T (p.Thr213=) rs139949679
NM_002691.3(POLD1):c.651G>A (p.Pro217=) rs199622672
NM_002691.3(POLD1):c.653G>A (p.Arg218His) rs150010804
NM_002691.3(POLD1):c.663C>A (p.Ala221=) rs778927849
NM_002691.3(POLD1):c.666G>A (p.Pro222=) rs746678748
NM_002691.3(POLD1):c.714G>A (p.Thr238=) rs149096523
NM_002691.3(POLD1):c.735G>A (p.Glu245=) rs745841154
NM_002691.3(POLD1):c.758+4C>T rs771346692
NM_002691.3(POLD1):c.773C>T (p.Thr258Met) rs76131127
NM_002691.3(POLD1):c.778A>G (p.Ile260Val) rs8105725
NM_002691.3(POLD1):c.783C>T (p.Val261=) rs34269084
NM_002691.3(POLD1):c.798G>A (p.Leu266=) rs1017934812
NM_002691.3(POLD1):c.80A>T (p.Asp27Val) rs150066950
NM_002691.3(POLD1):c.840+10T>C rs1555790184
NM_002691.3(POLD1):c.841-10A>G rs140160345
NM_002691.3(POLD1):c.841-5C>T rs530091118
NM_002691.3(POLD1):c.849G>T (p.Gln283His) rs113282414
NM_002691.3(POLD1):c.883G>A (p.Val295Met) rs199545019
NM_002691.3(POLD1):c.885G>C (p.Val295=) rs201946114
NM_002691.3(POLD1):c.88C>T (p.Arg30Trp) rs3218772
NM_002691.3(POLD1):c.945C>T (p.Phe315=) rs150116169
NM_002691.3(POLD1):c.957C>T (p.Cys319=) rs377300843
NM_002691.3(POLD1):c.971-4G>A rs200144991
NM_002691.3(POLD1):c.971-5C>T rs778993986
NM_002691.3(POLD1):c.99A>G (p.Gln33=) rs751090809

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