Variants in gene POLR3A with conflicting interpretations "likely pathogenic" and "pathogenic"

Submission 1 (likely pathogenic) minimum review status:		Submission 1 (likely pathogenic) method:
Submission 2 (pathogenic) minimum review status:		Submission 2 (pathogenic) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 21

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HGVS	dbSNP	gnomAD frequency
NM_007055.4(POLR3A):c.1909+22G>A	rs191875469	0.00156
NM_007055.4(POLR3A):c.760C>T (p.Arg254Ter)	rs141659018	0.00004
NM_007055.4(POLR3A):c.1572+1G>A	rs141484643	0.00003
NM_007055.4(POLR3A):c.2617-1G>A	rs181087667	0.00002
NM_007055.4(POLR3A):c.1048+5G>T	rs890755853	0.00001
NM_007055.4(POLR3A):c.2005C>T (p.Arg669Ter)	rs774007232	0.00001
NM_007055.4(POLR3A):c.2015G>A (p.Gly672Glu)	rs267608670	0.00001
NM_007055.4(POLR3A):c.2119C>T (p.Gln707Ter)	rs780839834	0.00001
NM_007055.4(POLR3A):c.2422C>T (p.Arg808Ter)	rs750874617	0.00001
NM_007055.4(POLR3A):c.3337-11T>C	rs1564613755	0.00001
NM_007055.4(POLR3A):c.3337-5T>A	rs368905417	0.00001
NM_007055.4(POLR3A):c.3655G>T (p.Gly1219Ter)	rs755978559	0.00001
NM_007055.4(POLR3A):c.*18C>T	rs1248039821
NM_007055.4(POLR3A):c.1771-7C>G	rs201314157
NM_007055.4(POLR3A):c.1800C>T (p.Ile600=)	rs1564620047
NM_007055.4(POLR3A):c.2474C>G (p.Ser825Ter)	rs1564617848
NM_007055.4(POLR3A):c.2554A>G (p.Met852Val)	rs267608671
NM_007055.4(POLR3A):c.2988+1G>A	rs201733323
NM_007055.4(POLR3A):c.3583del (p.Asp1195fs)	rs747683665
NM_007055.4(POLR3A):c.3G>T (p.Met1Ile)	rs1168641193
NM_007055.4(POLR3A):c.4003G>A (p.Gly1335Arg)	rs768222183

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