ClinVar Miner

Variants in gene combination RAD51D, RAD51L3-RFFL with conflicting interpretations reported as "likely benign and "uncertain significance"

Submission 1 (likely benign) minimum review status: Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 55
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HGVS dbSNP gnomAD frequency
NM_002878.4(RAD51D):c.568G>A (p.Ala190Thr) rs80116829 0.00167
NM_002878.4(RAD51D):c.146C>T (p.Ala49Val) rs140317560 0.00116
NM_002878.4(RAD51D):c.919G>A (p.Glu307Lys) rs115031549 0.00083
NM_002878.4(RAD51D):c.932T>A (p.Ile311Asn) rs145309168 0.00041
NM_002878.4(RAD51D):c.904-11T>A rs374449943 0.00038
NM_002878.4(RAD51D):c.26G>C (p.Cys9Ser) rs140825795 0.00037
NM_002878.4(RAD51D):c.413A>G (p.Asn138Ser) rs201676898 0.00025
NM_002878.4(RAD51D):c.983C>T (p.Thr328Ile) rs138969595 0.00021
NM_002878.4(RAD51D):c.904-3C>T rs45478491 0.00018
NM_002878.4(RAD51D):c.137C>G (p.Ser46Cys) rs587780102 0.00010
NM_002878.4(RAD51D):c.196G>A (p.Val66Met) rs56026142 0.00009
NM_002878.4(RAD51D):c.864C>T (p.Gly288=) rs138557828 0.00009
NM_002878.4(RAD51D):c.355T>C (p.Cys119Arg) rs201313861 0.00008
NM_002878.4(RAD51D):c.394G>A (p.Val132Ile) rs201141245 0.00007
NM_002878.4(RAD51D):c.145-4G>A rs201361465 0.00006
NM_002878.4(RAD51D):c.263+1641C>T rs142387263 0.00006
NM_002878.4(RAD51D):c.715C>T (p.Arg239Trp) rs770250516 0.00006
NM_002878.4(RAD51D):c.346-10C>T rs779972784 0.00005
NM_002878.4(RAD51D):c.145-13G>T rs760867838 0.00004
NM_002878.4(RAD51D):c.264-7C>T rs753529790 0.00004
NM_002878.4(RAD51D):c.796C>T (p.Arg266Cys) rs587781813 0.00004
NM_002878.4(RAD51D):c.481-8C>T rs762247126 0.00003
NM_002878.4(RAD51D):c.878C>T (p.Ala293Val) rs769732230 0.00003
NM_002878.4(RAD51D):c.915C>G (p.Phe305Leu) rs1316114457 0.00003
NM_002878.4(RAD51D):c.171G>A (p.Leu57=) rs786202885 0.00002
NM_002878.4(RAD51D):c.346-4C>G rs767328693 0.00002
NM_002878.4(RAD51D):c.738+3G>A rs751062153 0.00002
NM_002878.4(RAD51D):c.739-5T>C rs777400873 0.00002
NM_002878.4(RAD51D):c.144+3G>T rs761057565 0.00001
NM_002878.4(RAD51D):c.145-3C>T rs201974522 0.00001
NM_002878.4(RAD51D):c.22C>T (p.Leu8=) rs876659203 0.00001
NM_002878.4(RAD51D):c.345+5A>G rs878854562 0.00001
NM_002878.4(RAD51D):c.481-5T>G rs374382703 0.00001
NM_002878.4(RAD51D):c.49A>G (p.Ile17Val) rs1002032036 0.00001
NM_002878.4(RAD51D):c.70A>G (p.Arg24Gly) rs781611267 0.00001
NM_002878.4(RAD51D):c.739-3C>T rs1235042092 0.00001
NM_002878.4(RAD51D):c.776G>A (p.Arg259Lys) rs771473156 0.00001
NM_002878.4(RAD51D):c.80C>A (p.Thr27Lys) rs139642328 0.00001
NM_002878.4(RAD51D):c.865G>A (p.Gly289Ser) rs587782129 0.00001
NM_002878.4(RAD51D):c.869G>A (p.Arg290Gln) rs773883374 0.00001
NM_002878.4(RAD51D):c.904-13C>A rs964696175 0.00001
NM_002878.4(RAD51D):c.-7G>A rs553444507
NM_002878.4(RAD51D):c.145-4G>T rs201361465
NM_002878.4(RAD51D):c.145-4_145-3delinsTT rs786202099
NM_002878.4(RAD51D):c.163C>T (p.Arg55Trp) rs775268017
NM_002878.4(RAD51D):c.196G>T (p.Val66Leu) rs56026142
NM_002878.4(RAD51D):c.345+4C>T rs918947511
NM_002878.4(RAD51D):c.345+5A>T rs878854562
NM_002878.4(RAD51D):c.345+6T>C rs1555568466
NM_002878.4(RAD51D):c.412A>C (p.Asn138His) rs141690729
NM_002878.4(RAD51D):c.481-4T>G rs876659339
NM_002878.4(RAD51D):c.577-6C>A rs1210749655
NM_002878.4(RAD51D):c.668-13CCT[4] rs1230625396
NM_002878.4(RAD51D):c.691G>T (p.Ala231Ser) rs772135704
NM_002878.4(RAD51D):c.751A>G (p.Ile251Val) rs540273429

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