ClinVar Miner

Variants in gene RAF1 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
422 42 0 27 15 0 5 41

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 11 2 0 0
likely pathogenic 11 0 2 1 0
uncertain significance 2 2 0 13 7
likely benign 0 1 13 0 16
benign 0 0 7 16 0

All variants with conflicting interpretations #

Total variants: 41
Download table as spreadsheet
NM_001354689.3(RAF1):c.1168+9_1168+21del rs727504451
NM_001354689.3(RAF1):c.1173T>C (p.Asp391=) rs146668293
NM_001354689.3(RAF1):c.1200C>T (p.Val400=) rs397516814
NM_001354689.3(RAF1):c.1201G>A (p.Asp401Asn) rs559632360
NM_001354689.3(RAF1):c.122G>A (p.Arg41Gln) rs145611571
NM_001354689.3(RAF1):c.1232G>T (p.Arg411Met) rs587782972
NM_001354689.3(RAF1):c.124_125delinsAT (p.Ala42Ile) rs876657965
NM_001354689.3(RAF1):c.1532C>T (p.Thr511Ile) rs80338799
NM_001354689.3(RAF1):c.1689G>C (p.Thr563=) rs5746244
NM_001354689.3(RAF1):c.1728+10_1728+11del rs730880997
NM_001354689.3(RAF1):c.1728+19G>T rs5746245
NM_001354689.3(RAF1):c.1728+4A>G rs771344560
NM_001354689.3(RAF1):c.1781A>G (p.Tyr594Cys) rs370242565
NM_001354689.3(RAF1):c.1890A>G (p.Gln630=) rs141791080
NM_001354689.3(RAF1):c.1897C>G (p.Leu633Val) rs80338797
NM_001354689.3(RAF1):c.1931C>G (p.Ser644Cys) rs1057524239
NM_001354689.3(RAF1):c.1973C>T (p.Thr658Met) rs730881007
NM_001354689.3(RAF1):c.212A>G (p.Asn71Ser) rs184022679
NM_001354689.3(RAF1):c.524A>G (p.His175Arg) rs397516822
NM_001354689.3(RAF1):c.570C>T (p.Ile190=) rs780912024
NM_001354689.3(RAF1):c.581+4A>G rs201776526
NM_001354689.3(RAF1):c.639T>C (p.Thr213=) rs397516823
NM_001354689.3(RAF1):c.66T>G (p.Phe22Leu) rs397516824
NM_001354689.3(RAF1):c.680+6T>C rs371846795
NM_001354689.3(RAF1):c.766A>G (p.Arg256Gly) rs397516825
NM_001354689.3(RAF1):c.770C>T (p.Ser257Leu) rs80338796
NM_001354689.3(RAF1):c.775T>A (p.Ser259Thr) rs3730271
NM_001354689.3(RAF1):c.775T>G (p.Ser259Ala) rs3730271
NM_001354689.3(RAF1):c.779C>T (p.Thr260Ile) rs869025501
NM_001354689.3(RAF1):c.781C>G (p.Pro261Ala) rs121434594
NM_001354689.3(RAF1):c.781C>T (p.Pro261Ser) rs121434594
NM_001354689.3(RAF1):c.782C>G (p.Pro261Arg) rs397516828
NM_001354689.3(RAF1):c.782C>T (p.Pro261Leu) rs397516828
NM_001354689.3(RAF1):c.785A>T (p.Asn262Ile) rs730881010
NM_001354689.3(RAF1):c.788T>G (p.Val263Gly) rs397516830
NM_001354689.3(RAF1):c.895G>A (p.Asp299Asn) rs368796800
NM_001354689.3(RAF1):c.94A>G (p.Ile32Val) rs372738063
NM_001354689.3(RAF1):c.967A>G (p.Thr323Ala) rs775898894
NM_001354689.3(RAF1):c.969A>C (p.Thr323=) rs5746219
NM_001354689.3(RAF1):c.983C>T (p.Pro328Leu) rs5746220
NM_001354689.3(RAF1):c.995T>C (p.Val332Ala) rs370243307

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