Variants in gene SMAD3 with conflicting interpretations "pathogenic" and "likely pathogenic"

Submission 1 (pathogenic) minimum review status:		Submission 1 (pathogenic) method:
Submission 2 (likely pathogenic) minimum review status:		Submission 2 (likely pathogenic) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 17

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HGVS	dbSNP	gnomAD frequency
NM_005902.4(SMAD3):c.220C>T (p.Arg74Trp)	rs1343295267	0.00001
NM_005902.4(SMAD3):c.1117C>T (p.Arg373Cys)	rs863223746
NM_005902.4(SMAD3):c.1118G>A (p.Arg373His)	rs1060500766
NM_005902.4(SMAD3):c.1139G>A (p.Trp380Ter)
NM_005902.4(SMAD3):c.1166_1167del (p.Val389fs)	rs1595965925
NM_005902.4(SMAD3):c.1268G>A (p.Ser423Asn)	rs1555414503
NM_005902.4(SMAD3):c.269G>A (p.Arg90His)	rs886038803
NM_005902.4(SMAD3):c.278G>A (p.Arg93Gln)	rs863223765
NM_005902.4(SMAD3):c.401-6G>A	rs745672741
NM_005902.4(SMAD3):c.715G>A (p.Glu239Lys)	rs387906853
NM_005902.4(SMAD3):c.727C>T (p.Arg243Cys)	rs886039137
NM_005902.4(SMAD3):c.733G>A (p.Gly245Arg)	rs863223737
NM_005902.4(SMAD3):c.733G>C (p.Gly245Arg)	rs863223737
NM_005902.4(SMAD3):c.788C>T (p.Pro263Leu)	rs387906855
NM_005902.4(SMAD3):c.802C>T (p.Arg268Cys)	rs794727798
NM_005902.4(SMAD3):c.803G>A (p.Arg268His)	rs863223740
NM_005902.4(SMAD3):c.860G>A (p.Arg287Gln)	rs730880214

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