Variants in gene SPAST with conflicting interpretations "likely pathogenic" and "uncertain significance"

Submission 1 (likely pathogenic) minimum review status:		Submission 1 (likely pathogenic) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 12

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HGVS	dbSNP	gnomAD frequency
NM_014946.4(SPAST):c.1625A>G (p.Asp542Gly)	rs142053576	0.00024
NM_014946.4(SPAST):c.631G>A (p.Val211Ile)	rs143003434	0.00002
NM_014946.4(SPAST):c.1783A>G (p.Ser595Gly)	rs1553321245	0.00001
NM_014946.4(SPAST):c.1817G>A (p.Arg606His)	rs768077366	0.00001
NM_014946.4(SPAST):c.1173G>A (p.Leu391=)	rs1679218212
NM_014946.4(SPAST):c.1174G>C (p.Ala392Pro)	rs1558331867
NM_014946.4(SPAST):c.1450G>C (p.Gly484Arg)	rs1553318317
NM_014946.4(SPAST):c.1477G>C (p.Asp493His)	rs1060499939
NM_014946.4(SPAST):c.1537-11A>G	rs549538513
NM_014946.4(SPAST):c.1762T>C (p.Ser588Pro)	rs1131691972
NM_014946.4(SPAST):c.1785C>A (p.Ser595Arg)	rs145206063
Single allele

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