Variants in gene SPG7 with conflicting interpretations "uncertain significance" and "likely pathogenic"

Submission 1 (uncertain significance) minimum review status:		Submission 1 (uncertain significance) method:
Submission 2 (likely pathogenic) minimum review status:		Submission 2 (likely pathogenic) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 11

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HGVS	dbSNP	gnomAD frequency
NM_003119.4(SPG7):c.1586C>T (p.Ala529Val)	rs748600162	0.00011
NM_003119.4(SPG7):c.1552+2dup	rs1567928509	0.00001
NM_003119.4(SPG7):c.1972G>A (p.Ala658Thr)	rs2058661391	0.00001
NM_003119.4(SPG7):c.2104G>A (p.Glu702Lys)	rs752257333	0.00001
NM_003119.4(SPG7):c.1033G>C (p.Ala345Pro)	rs368373840
NM_003119.4(SPG7):c.1727C>G (p.Ser576Trp)	rs151249432
NM_003119.4(SPG7):c.1894G>A (p.Gly632Arg)	rs368541637
NM_003119.4(SPG7):c.1904C>T (p.Ser635Leu)	rs864622507
NM_003119.4(SPG7):c.1931C>T (p.Thr644Ile)	rs758702550
NM_003119.4(SPG7):c.2161A>G (p.Asn721Asp)	rs2152412388
NM_003119.4(SPG7):c.2246C>T (p.Pro749Leu)

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