ClinVar Miner

Variants in gene SPTAN1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
448 51 0 62 64 0 6 118

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 3 4 2
likely pathogenic 1 0 0 1 1
uncertain significance 3 0 0 55 18
likely benign 4 1 55 0 61
benign 2 1 18 61 0

All variants with conflicting interpretations #

Total variants: 118
Download table as spreadsheet
HGVS dbSNP
NM_001130438.2(SPTAN1):c.1086-4C>G rs367718622
NM_001130438.2(SPTAN1):c.1221+11C>T rs113357847
NM_001130438.2(SPTAN1):c.1303T>G (p.Ser435Ala) rs144787939
NM_001130438.2(SPTAN1):c.1330G>A (p.Val444Ile) rs77358650
NM_001130438.2(SPTAN1):c.1339G>A (p.Glu447Lys) rs767067922
NM_001130438.2(SPTAN1):c.1348G>T (p.Ala450Ser) rs768940761
NM_001130438.2(SPTAN1):c.1511C>T (p.Ala504Val) rs148727077
NM_001130438.2(SPTAN1):c.1621A>G (p.Met541Val) rs796053315
NM_001130438.2(SPTAN1):c.1737C>T (p.Phe579=) rs143941068
NM_001130438.2(SPTAN1):c.1806+15G>T rs372203791
NM_001130438.2(SPTAN1):c.1806+4A>G rs770046688
NM_001130438.2(SPTAN1):c.1807-11T>C rs139049596
NM_001130438.2(SPTAN1):c.1968G>A (p.Val656=) rs968327265
NM_001130438.2(SPTAN1):c.2011+10G>A rs377437879
NM_001130438.2(SPTAN1):c.2163C>A (p.Ala721=) rs10760566
NM_001130438.2(SPTAN1):c.2194-13T>G rs28676915
NM_001130438.2(SPTAN1):c.2233C>A (p.Gln745Lys) rs769094437
NM_001130438.2(SPTAN1):c.2343C>A (p.Ala781=) rs34084388
NM_001130438.2(SPTAN1):c.237+4C>T rs371350283
NM_001130438.2(SPTAN1):c.2599G>A (p.Glu867Lys) rs1339046005
NM_001130438.2(SPTAN1):c.2610A>G (p.Gln870=) rs138101005
NM_001130438.2(SPTAN1):c.2700C>T (p.Asn900=) rs147466898
NM_001130438.2(SPTAN1):c.2753A>G (p.Tyr918Cys) rs138275607
NM_001130438.2(SPTAN1):c.2880G>A (p.Val960=) rs150731568
NM_001130438.2(SPTAN1):c.2889G>A (p.Thr963=) rs34654141
NM_001130438.2(SPTAN1):c.3042T>G (p.Gly1014=) rs150870424
NM_001130438.2(SPTAN1):c.3051G>A (p.Pro1017=) rs140279996
NM_001130438.2(SPTAN1):c.3057G>A (p.Ala1019=) rs759833805
NM_001130438.2(SPTAN1):c.3060C>T (p.Tyr1020=) rs530361602
NM_001130438.2(SPTAN1):c.3078C>T (p.Pro1026=) rs779993051
NM_001130438.2(SPTAN1):c.3099G>T (p.Glu1033Asp) rs374682395
NM_001130438.2(SPTAN1):c.3215+15_3215+16delAG rs551595039
NM_001130438.2(SPTAN1):c.3300G>A (p.Ala1100=) rs2227865
NM_001130438.2(SPTAN1):c.3337G>A (p.Ala1113Thr) rs143309753
NM_001130438.2(SPTAN1):c.3415-9G>T rs199802986
NM_001130438.2(SPTAN1):c.3520-14C>G rs142682344
NM_001130438.2(SPTAN1):c.3546T>C (p.Asp1182=) rs945831
NM_001130438.2(SPTAN1):c.3579+3_3579+4dup rs797046004
NM_001130438.2(SPTAN1):c.3673C>T (p.Arg1225Trp) rs569997507
NM_001130438.2(SPTAN1):c.3720-5T>G rs200543425
NM_001130438.2(SPTAN1):c.3720-7C>T rs773023641
NM_001130438.2(SPTAN1):c.3762A>G (p.Gln1254=) rs533042543
NM_001130438.2(SPTAN1):c.3803T>C (p.Val1268Ala) rs146153626
NM_001130438.2(SPTAN1):c.3849G>A (p.Ala1283=) rs117614529
NM_001130438.2(SPTAN1):c.3912C>T (p.Pro1304=) rs143844598
NM_001130438.2(SPTAN1):c.4039G>A (p.Asp1347Asn) rs574740801
NM_001130438.2(SPTAN1):c.4045C>T (p.Arg1349Trp) rs771862017
NM_001130438.2(SPTAN1):c.4046+4C>T rs370704701
NM_001130438.2(SPTAN1):c.4046+5G>A rs541570752
NM_001130438.2(SPTAN1):c.4047-14G>T rs558154123
NM_001130438.2(SPTAN1):c.4116C>T (p.Thr1372=) rs148554113
NM_001130438.2(SPTAN1):c.4188G>A (p.Gln1396=) rs763156575
NM_001130438.2(SPTAN1):c.4199A>T (p.Gln1400Leu) rs143108250
NM_001130438.2(SPTAN1):c.4260T>G (p.Leu1420=) rs146150071
NM_001130438.2(SPTAN1):c.4283C>G (p.Ala1428Gly) rs143166100
NM_001130438.2(SPTAN1):c.4310G>A (p.Arg1437His) rs752347538
NM_001130438.2(SPTAN1):c.4410C>T (p.Thr1470=) rs2228951
NM_001130438.2(SPTAN1):c.4536C>T (p.Ile1512=) rs367772623
NM_001130438.2(SPTAN1):c.4543G>A (p.Gly1515Ser) rs149899658
NM_001130438.2(SPTAN1):c.4580A>G (p.Asn1527Ser) rs145038571
NM_001130438.2(SPTAN1):c.4595+4G>T rs185925523
NM_001130438.2(SPTAN1):c.4604G>A (p.Arg1535His) rs745394212
NM_001130438.2(SPTAN1):c.4785G>A (p.Gln1595=) rs746824729
NM_001130438.2(SPTAN1):c.5044-4C>T rs749484552
NM_001130438.2(SPTAN1):c.5106G>A (p.Leu1702=) rs373491498
NM_001130438.2(SPTAN1):c.5149-10C>T rs587784437
NM_001130438.2(SPTAN1):c.5245G>A (p.Gly1749Arg) rs771886198
NM_001130438.2(SPTAN1):c.5415G>A (p.Gln1805=) rs142964132
NM_001130438.2(SPTAN1):c.5437C>A (p.Arg1813=) rs3750333
NM_001130438.2(SPTAN1):c.5460G>A (p.Ala1820=) rs140191388
NM_001130438.2(SPTAN1):c.5478+12G>A rs41275900
NM_001130438.2(SPTAN1):c.5523C>T (p.Ile1841=) rs79569204
NM_001130438.2(SPTAN1):c.5724C>T (p.Ala1908=) rs886063507
NM_001130438.2(SPTAN1):c.5775C>T (p.Thr1925=) rs140353002
NM_001130438.2(SPTAN1):c.5790C>T (p.Arg1930=) rs144435438
NM_001130438.2(SPTAN1):c.5925G>A (p.Ala1975=) rs11543345
NM_001130438.2(SPTAN1):c.6042T>G (p.Ser2014=) rs142830725
NM_001130438.2(SPTAN1):c.6111C>T (p.Gly2037=) rs139799727
NM_001130438.2(SPTAN1):c.6159C>T (p.His2053=) rs150902677
NM_001130438.2(SPTAN1):c.6190G>A (p.Ala2064Thr) rs201411901
NM_001130438.2(SPTAN1):c.6213C>G (p.Ser2071Arg) rs754910706
NM_001130438.2(SPTAN1):c.6234C>T (p.Ala2078=) rs147132904
NM_001130438.2(SPTAN1):c.6235G>A (p.Ala2079Thr) rs377253398
NM_001130438.2(SPTAN1):c.6417C>T (p.Asp2139=) rs140418358
NM_001130438.2(SPTAN1):c.641A>G (p.Lys214Arg) rs760419507
NM_001130438.2(SPTAN1):c.6488A>G (p.Lys2163Arg) rs144289764
NM_001130438.2(SPTAN1):c.6498C>A (p.Arg2166=) rs72758823
NM_001130438.2(SPTAN1):c.6498C>T (p.Arg2166=) rs72758823
NM_001130438.2(SPTAN1):c.6549C>A (p.Thr2183=) rs116778543
NM_001130438.2(SPTAN1):c.6654C>T (p.His2218=) rs372825476
NM_001130438.2(SPTAN1):c.6660C>T (p.Asn2220=) rs112955915
NM_001130438.2(SPTAN1):c.6708-7C>T rs16930539
NM_001130438.2(SPTAN1):c.6763C>T (p.Arg2255Cys) rs372779649
NM_001130438.2(SPTAN1):c.6876C>T (p.Thr2292=) rs886063509
NM_001130438.2(SPTAN1):c.6908_6916delACCAGCTGG (p.Asp2303_Leu2305del) rs587784440
NM_001130438.2(SPTAN1):c.6908_6916dupACCAGCTGG (p.Leu2305_Gly2306insAspGlnLeu) rs587784440
NM_001130438.2(SPTAN1):c.6960-8T>C rs140241053
NM_001130438.2(SPTAN1):c.7090C>T (p.Leu2364=) rs374893683
NM_001130438.2(SPTAN1):c.7102G>C (p.Glu2368Gln) rs796053329
NM_001130438.2(SPTAN1):c.7135A>G (p.Ile2379Val) rs770358940
NM_001130438.2(SPTAN1):c.7146G>A (p.Thr2382=) rs75028792
NM_001130438.2(SPTAN1):c.7155G>A (p.Pro2385=) rs200456378
NM_001130438.2(SPTAN1):c.7160+10_7160+13delTTAA rs554161838
NM_001130438.2(SPTAN1):c.7161-8G>A rs202180736
NM_001130438.2(SPTAN1):c.7161-9C>T rs187613754
NM_001130438.2(SPTAN1):c.7233C>T (p.Ser2411=) rs138985089
NM_001130438.2(SPTAN1):c.7284C>T (p.Tyr2428=) rs201348505
NM_001130438.2(SPTAN1):c.7309-12_7309-11delCT rs770948927
NM_001130438.2(SPTAN1):c.7319G>A (p.Arg2440Gln) rs141980692
NM_001130438.2(SPTAN1):c.7359C>T (p.Tyr2453=) rs138634476
NM_001130438.2(SPTAN1):c.7366G>A (p.Gly2456Ser) rs199866550
NM_001130438.2(SPTAN1):c.7389C>T (p.Thr2463=) rs2228952
NM_001130438.2(SPTAN1):c.7392G>A (p.Ala2464=) rs149318543
NM_001130438.2(SPTAN1):c.7396G>A (p.Asp2466Asn) rs367776636
NM_001130438.2(SPTAN1):c.7419G>A (p.Ser2473=) rs375649697
NM_001130438.2(SPTAN1):c.774G>A (p.Gln258=) rs138609094
NM_001130438.2(SPTAN1):c.862G>C (p.Ala288Pro) rs796053298
NM_001130438.2(SPTAN1):c.979C>T (p.Leu327=) rs587784442

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