ClinVar Miner

Variants in gene STK11 with conflicting interpretations "uncertain significance" and "benign"

Submission 1 (uncertain significance) minimum review status: Submission 1 (uncertain significance) method:
Submission 2 (benign) minimum review status: Submission 2 (benign) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 55
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HGVS dbSNP gnomAD frequency
NM_000455.5(STK11):c.920+7G>C rs2075607 0.16357
NM_000455.5(STK11):c.894C>A (p.Phe298Leu) rs199681533 0.00100
NM_000455.5(STK11):c.1211C>T (p.Ser404Phe) rs200078204 0.00051
NM_000455.5(STK11):c.1185A>G (p.Thr395=) rs370207155 0.00047
NM_000455.5(STK11):c.1284G>A (p.Ser428=) rs369097329 0.00035
NM_000455.5(STK11):c.*8C>T rs587782259 0.00027
NM_000455.5(STK11):c.618G>A (p.Ala206=) rs370976710 0.00018
NM_000455.5(STK11):c.825G>A (p.Pro275=) rs202011521 0.00011
NM_000455.5(STK11):c.-2G>T rs774072752 0.00007
NM_000455.5(STK11):c.357C>T (p.Asn119=) rs372511774 0.00007
NM_000455.5(STK11):c.734+20G>A rs375315233 0.00007
NM_000455.5(STK11):c.125G>T (p.Arg42Leu) rs148830698 0.00006
NM_000455.5(STK11):c.842C>T (p.Pro281Leu) rs121913322 0.00006
NM_000455.5(STK11):c.1254C>G (p.Cys418Trp) rs587780715 0.00005
NM_000455.5(STK11):c.465-5C>T rs567202367 0.00005
NM_000455.5(STK11):c.970C>G (p.Pro324Ala) rs549474196 0.00005
NM_000455.5(STK11):c.1109-5C>T rs587782020 0.00004
NM_000455.5(STK11):c.612C>T (p.Phe204=) rs774100153 0.00004
NM_000455.5(STK11):c.631C>T (p.Arg211Trp) rs185087320 0.00004
NM_000455.5(STK11):c.1193C>T (p.Ala398Val) rs768058962 0.00003
NM_000455.5(STK11):c.1226G>A (p.Arg409Gln) rs587782364 0.00003
NM_000455.5(STK11):c.1168G>A (p.Val390Met) rs374078532 0.00002
NM_000455.5(STK11):c.310A>G (p.Arg104Gly) rs587782783 0.00002
NM_000455.5(STK11):c.828C>T (p.Gly276=) rs200824447 0.00002
NM_000455.5(STK11):c.901C>T (p.Arg301Trp) rs587780012 0.00002
NM_000455.5(STK11):c.1129G>A (p.Ala377Thr) rs768870802 0.00001
NM_000455.5(STK11):c.1135C>A (p.His379Asn) rs762124698 0.00001
NM_000455.5(STK11):c.1148G>A (p.Arg383His) rs730881990 0.00001
NM_000455.5(STK11):c.1175T>C (p.Met392Thr) rs876661013 0.00001
NM_000455.5(STK11):c.1195C>A (p.Gln399Lys) rs1060499968 0.00001
NM_000455.5(STK11):c.1208A>G (p.Lys403Arg) rs587781633 0.00001
NM_000455.5(STK11):c.1274G>A (p.Arg425His) rs730881992 0.00001
NM_000455.5(STK11):c.1276C>T (p.Arg426Trp) rs587782687 0.00001
NM_000455.5(STK11):c.1283C>T (p.Ser428Leu) rs587781537 0.00001
NM_000455.5(STK11):c.434A>G (p.Glu145Gly) rs369764220 0.00001
NM_000455.5(STK11):c.449T>C (p.Val150Ala) rs587781802 0.00001
NM_000455.5(STK11):c.464+8C>T rs863224669 0.00001
NM_000455.5(STK11):c.579C>T (p.Ser193=) rs730881961 0.00001
NM_000455.5(STK11):c.841C>A (p.Pro281Thr) rs377208033 0.00001
NM_000455.5(STK11):c.863-4T>C rs778853572 0.00001
NM_000455.5(STK11):c.921-8G>A rs863224362 0.00001
NM_000455.5(STK11):c.947C>G (p.Ala316Gly) rs751709130 0.00001
NM_000455.5(STK11):c.94A>G (p.Thr32Ala) rs755210880 0.00001
NM_000455.5(STK11):c.957A>G (p.Pro319=) rs755126393 0.00001
NM_000455.5(STK11):c.-107dup rs927999961
NM_000455.5(STK11):c.1129G>C (p.Ala377Pro) rs768870802
NM_000455.5(STK11):c.1180G>A (p.Gly394Ser) rs768780695
NM_000455.5(STK11):c.120C>T (p.Arg40=) rs878853984
NM_000455.5(STK11):c.1243C>G (p.Arg415Gly) rs864622448
NM_000455.5(STK11):c.1276C>G (p.Arg426Gly) rs587782687
NM_000455.5(STK11):c.1286C>T (p.Ala429Val) rs757369900
NM_000455.5(STK11):c.465-4G>A rs587780009
NM_000455.5(STK11):c.617C>T (p.Ala206Val) rs764244639
NM_000455.5(STK11):c.734+19dup rs730881962
NM_000455.5(STK11):c.842C>A (p.Pro281Gln) rs121913322

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