ClinVar Miner

Variants in gene TNFRSF1A with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
204 33 0 4 16 1 2 18

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign drug response protective other
pathogenic 0 2 1 0 1 0 0 0
likely pathogenic 2 0 1 0 1 0 0 0
uncertain significance 2 2 0 12 6 1 1 1
likely benign 0 0 11 0 3 0 0 0
benign 1 1 5 3 0 0 0 0

All variants with conflicting interpretations #

Total variants: 18
Download table as spreadsheet
HGVS dbSNP
NM_001065.3(TNFRSF1A):c.472+7G>T rs200194581
NM_001065.4(TNFRSF1A):c.1110C>T (p.Arg370=) rs201683984
NM_001065.4(TNFRSF1A):c.1206C>T (p.Ser402=) rs148334665
NM_001065.4(TNFRSF1A):c.123T>G (p.Asp41Glu) rs104895271
NM_001065.4(TNFRSF1A):c.1328G>T (p.Gly443Val) rs201062001
NM_001065.4(TNFRSF1A):c.1329C>A (p.Gly443=) rs756455040
NM_001065.4(TNFRSF1A):c.224C>T (p.Pro75Leu) rs4149637
NM_001065.4(TNFRSF1A):c.255G>C (p.Glu85Asp) rs770439546
NM_001065.4(TNFRSF1A):c.269C>T (p.Thr90Ile) rs34751757
NM_001065.4(TNFRSF1A):c.362G>A (p.Arg121Gln) rs4149584
NM_001065.4(TNFRSF1A):c.369C>T (p.Thr123=) rs104895260
NM_001065.4(TNFRSF1A):c.36A>G (p.Pro12=) rs767455
NM_001065.4(TNFRSF1A):c.492C>T (p.Thr164=)
NM_001065.4(TNFRSF1A):c.625+10A>G rs1800693
NM_001065.4(TNFRSF1A):c.645C>T (p.Pro215=) rs147075345
NM_001065.4(TNFRSF1A):c.753G>A (p.Ser251=) rs201358363
NM_001065.4(TNFRSF1A):c.935G>A (p.Arg312Lys) rs200900510
Single allele

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