Variants in gene TNNT2 with conflicting interpretations "likely pathogenic" and "uncertain significance"

Submission 1 (likely pathogenic) minimum review status:		Submission 1 (likely pathogenic) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 16

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_001276345.2(TNNT2):c.862C>T (p.Arg288Cys)	rs121964857	0.00044
NM_001276345.2(TNNT2):c.863G>A (p.Arg288His)	rs397516484	0.00005
NM_001276345.2(TNNT2):c.460C>T (p.Arg154Trp)	rs483352832	0.00003
NM_001276345.2(TNNT2):c.277G>A (p.Glu93Lys)	rs727504244	0.00001
NM_001276345.2(TNNT2):c.452G>A (p.Arg151Gln)	rs730881101	0.00001
NM_001276345.2(TNNT2):c.601-1G>A	rs483352835	0.00001
NM_001276345.2(TNNT2):c.886C>T (p.Arg296Cys)	rs367785431	0.00001
NM_001276345.2(TNNT2):c.268C>T (p.Pro90Ser)	rs397516451
NM_001276345.2(TNNT2):c.286G>A (p.Asp96Asn)	rs1553282768
NM_001276345.2(TNNT2):c.321G>T (p.Lys107Asn)	rs397516459
NM_001276345.2(TNNT2):c.445C>T (p.Arg149Cys)	rs397516465
NM_001276345.2(TNNT2):c.446G>A (p.Arg149His)	rs397516466
NM_001276345.2(TNNT2):c.644G>A (p.Arg215Gln)	rs121964860
NM_001276345.2(TNNT2):c.764C>T (p.Ala255Val)	rs369181536
NM_001276345.2(TNNT2):c.851+5G>A	rs193922620
NM_001276345.2(TNNT2):c.863G>C (p.Arg288Pro)	rs397516484

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.