ClinVar Miner

Variants in gene TNXB with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic) 		Variants with a confidence conflict
(e.g. benign vs likely benign) 		Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects) 		Variants with a clinically significant conflict
(e.g. benign vs pathogenic) 		Variants with any conflict
2054 552 0 56 124 0 3 178

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 7 2 0 0
likely pathogenic 7 0 1 0 0
uncertain significance 2 1 0 122 5
likely benign 0 0 122 0 49
benign 0 0 5 49 0

All variants with conflicting interpretations #

Total variants: 178
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001365276.2(TNXB):c.8791+35G>A rs11969759 0.10162
NM_001365276.2(TNXB):c.7680C>T (p.Asp2560=) rs12196385 0.10077
NM_001365276.2(TNXB):c.3764G>A (p.Arg1255His) rs12211410 0.08362
NM_001365276.2(TNXB):c.8132T>C (p.Ile2711Thr) rs28361051 0.00963
NM_001365276.2(TNXB):c.6024A>G (p.Thr2008=) rs61744966 0.00962
NM_001365276.2(TNXB):c.7720A>G (p.Lys2574Glu) rs187409250 0.00902
NM_001365276.2(TNXB):c.7711C>G (p.Gln2571Glu) rs188116087 0.00897
NM_001365276.2(TNXB):c.7704T>C (p.Val2568=) rs370919547 0.00888
NM_001365276.2(TNXB):c.113G>A (p.Arg38Gln) rs149502087 0.00797
NM_001365276.2(TNXB):c.9849G>A (p.Thr3283=) rs147118175 0.00795
NM_001365276.2(TNXB):c.7297G>A (p.Val2433Ile) rs17207902 0.00594
NM_001365276.2(TNXB):c.2373C>T (p.Ser791=) rs112581362 0.00587
NM_001365276.2(TNXB):c.10018G>A (p.Gly3340Ser) rs61737606 0.00542
NM_001365276.2(TNXB):c.9072C>T (p.His3024=) rs61729739 0.00518
NM_001365276.2(TNXB):c.1837A>G (p.Ser613Gly) rs61744970 0.00512
NM_001365276.2(TNXB):c.7168+19C>A rs11752495 0.00484
NM_001365276.2(TNXB):c.5746A>G (p.Thr1916Ala) rs17207916 0.00455
NM_001365276.2(TNXB):c.3445+8A>G rs201624002 0.00326
NM_001365276.2(TNXB):c.4562C>T (p.Ala1521Val) rs146120469 0.00316
NM_001365276.2(TNXB):c.6811G>C (p.Val2271Leu) rs140770834 0.00309
NM_001365276.2(TNXB):c.8594T>C (p.Met2865Thr) rs373158501 0.00294
NM_001365276.2(TNXB):c.10368C>T (p.Thr3456=) rs116701346 0.00261
NM_001365276.2(TNXB):c.9612C>T (p.Asp3204=) rs61746872 0.00253
NM_001365276.2(TNXB):c.3272C>A (p.Ser1091Tyr) rs61978561 0.00214
NM_001365276.2(TNXB):c.909C>G (p.Gly303=) rs111244635 0.00214
NM_001365276.2(TNXB):c.9438G>A (p.Thr3146=) rs202162469 0.00200
NM_001365276.2(TNXB):c.7647T>C (p.Phe2549=) rs571377258 0.00183
NM_001365276.2(TNXB):c.4444G>A (p.Val1482Met) rs61740336 0.00179
NM_001365276.2(TNXB):c.7051G>A (p.Gly2351Arg) rs201638755 0.00166
NM_001365276.2(TNXB):c.2030A>G (p.Asp677Gly) rs141190850 0.00158
NM_001365276.2(TNXB):c.2945C>T (p.Thr982Ile) rs199569974 0.00146
NM_001365276.2(TNXB):c.10046-4C>T rs41267134 0.00141
NM_001365276.2(TNXB):c.2242+18C>G rs117489305 0.00139
NM_001365276.2(TNXB):c.6649C>A (p.Pro2217Thr) rs142409885 0.00139
NM_001365276.2(TNXB):c.2170C>T (p.Arg724Cys) rs138771398 0.00117
NM_001365276.2(TNXB):c.7866C>T (p.Thr2622=) rs4711284 0.00104
NM_001365276.2(TNXB):c.9663G>A (p.Val3221=) rs2242569 0.00102
NM_001365276.2(TNXB):c.7750C>T (p.Arg2584Cys) rs201690494 0.00096
NM_001365276.2(TNXB):c.5488A>C (p.Ser1830Arg) rs200519530 0.00088
NM_001365276.2(TNXB):c.7486G>A (p.Val2496Met) rs182362312 0.00084
NM_001365276.2(TNXB):c.9523A>T (p.Thr3175Ser) rs202109631 0.00078
NM_001365276.2(TNXB):c.2633G>A (p.Gly878Asp) rs201647307 0.00074
NM_001365276.2(TNXB):c.7856C>T (p.Pro2619Leu) rs183760368 0.00073
NM_001365276.2(TNXB):c.7413T>C (p.Pro2471=) rs375764263 0.00072
NM_001365276.2(TNXB):c.3488G>A (p.Gly1163Glu) rs185207099 0.00067
NM_001365276.2(TNXB):c.8285A>G (p.His2762Arg) rs376978176 0.00065
NM_001365276.2(TNXB):c.3322G>A (p.Val1108Met) rs121912575 0.00061
NM_001365276.2(TNXB):c.86G>A (p.Arg29Gln) rs184878358 0.00060
NM_001365276.2(TNXB):c.10111G>A (p.Val3371Met) rs201155046 0.00058
NM_001365276.2(TNXB):c.5103C>A (p.Phe1701Leu) rs201360247 0.00058
NM_001365276.2(TNXB):c.9762C>T (p.Pro3254=) rs190855421 0.00058
NM_001365276.2(TNXB):c.6074A>T (p.Asp2025Val) rs201397168 0.00055
NM_001365276.2(TNXB):c.6367G>A (p.Asp2123Asn) rs201764050 0.00054
NM_001365276.2(TNXB):c.7802C>T (p.Pro2601Leu) rs575866552 0.00053
NM_001365276.2(TNXB):c.3226G>A (p.Asp1076Asn) rs202227084 0.00050
NM_001365276.2(TNXB):c.6276C>T (p.Pro2092=) rs376343294 0.00050
NM_001365276.2(TNXB):c.1927A>G (p.Thr643Ala) rs201703963 0.00049
NM_001365276.2(TNXB):c.6608G>A (p.Arg2203Lys) rs150876029 0.00049
NM_001365276.2(TNXB):c.2995G>A (p.Glu999Lys) rs373054105 0.00048
NM_001365276.2(TNXB):c.8740G>A (p.Gly2914Ser) rs200708257 0.00048
NM_001365276.2(TNXB):c.5938G>A (p.Ala1980Thr) rs148556332 0.00044
NM_001365276.2(TNXB):c.8990G>A (p.Arg2997His) rs41270454 0.00043
NM_001365276.2(TNXB):c.8012C>T (p.Ala2671Val) rs201037895 0.00042
NM_001365276.2(TNXB):c.2947G>A (p.Ala983Thr) rs138850364 0.00038
NM_001365276.2(TNXB):c.2927G>A (p.Arg976His) rs200771983 0.00035
NM_001365276.2(TNXB):c.619G>A (p.Gly207Ser) rs139154852 0.00035
NM_001365276.2(TNXB):c.9617A>G (p.Gln3206Arg) rs201902411 0.00035
NM_001365276.2(TNXB):c.3149-3C>T rs372556970 0.00032
NM_001365276.2(TNXB):c.6135G>C (p.Leu2045=) rs149376928 0.00031
NM_001365276.2(TNXB):c.6598A>G (p.Met2200Val) rs373648872 0.00031
NM_001365276.2(TNXB):c.3277G>A (p.Val1093Met) rs200432719 0.00029
NM_001365276.2(TNXB):c.7352G>A (p.Arg2451Gln) rs201131695 0.00027
NM_001365276.2(TNXB):c.2485G>A (p.Gly829Ser) rs147172260 0.00024
NM_001365276.2(TNXB):c.6211G>A (p.Gly2071Arg) rs200319996 0.00024
NM_001365276.2(TNXB):c.8432G>A (p.Arg2811Gln) rs200522966 0.00024
NM_001365276.2(TNXB):c.2366G>A (p.Gly789Glu) rs367834992 0.00022
NM_001365276.2(TNXB):c.2623G>A (p.Val875Ile) rs377480086 0.00022
NM_001365276.2(TNXB):c.6358G>A (p.Gly2120Ser) rs777574450 0.00021
NM_001365276.2(TNXB):c.9121A>G (p.Lys3041Glu) rs376639281 0.00019
NM_001365276.2(TNXB):c.9439+8A>G rs200282568 0.00019
NM_001365276.2(TNXB):c.9661G>A (p.Val3221Met) rs367685759 0.00019
NM_001365276.2(TNXB):c.5155G>A (p.Val1719Met) rs200125936 0.00017
NM_001365276.2(TNXB):c.5870A>G (p.His1957Arg) rs760731362 0.00017
NM_001365276.2(TNXB):c.5965C>T (p.Arg1989Cys) rs371681556 0.00016
NM_001365276.2(TNXB):c.1480A>T (p.Thr494Ser) rs770149701 0.00015
NM_001365276.2(TNXB):c.2981G>A (p.Arg994His) rs372167278 0.00015
NM_001365276.2(TNXB):c.10156G>A (p.Val3386Met) rs530880273 0.00013
NM_001365276.2(TNXB):c.4894A>G (p.Ile1632Val) rs766602645 0.00013
NM_001365276.2(TNXB):c.5491G>A (p.Val1831Met) rs188124424 0.00013
NM_001365276.2(TNXB):c.7694C>T (p.Ala2565Val) rs199719197 0.00013
NM_001365276.2(TNXB):c.8761G>A (p.Val2921Met) rs529485424 0.00013
NM_001365276.2(TNXB):c.2390G>A (p.Arg797Gln) rs201123945 0.00012
NM_001365276.2(TNXB):c.9083G>A (p.Arg3028His) rs189416175 0.00012
NM_001365276.2(TNXB):c.10457C>T (p.Thr3486Met) rs368518664 0.00011
NM_001365276.2(TNXB):c.2730G>A (p.Ala910=) rs564894886 0.00011
NM_001365276.2(TNXB):c.3038G>A (p.Arg1013His) rs200322894 0.00011
NM_001365276.2(TNXB):c.9637A>G (p.Arg3213Gly) rs377386505 0.00011
NM_001365276.2(TNXB):c.9779C>T (p.Pro3260Leu) rs557119336 0.00011
NM_001365276.2(TNXB):c.10369G>T (p.Val3457Leu) rs199623625 0.00010
NM_001365276.2(TNXB):c.2540G>A (p.Arg847Gln) rs200283439 0.00010
NM_001365276.2(TNXB):c.1496G>A (p.Gly499Asp) rs771249673 0.00009
NM_001365276.2(TNXB):c.5268C>T (p.Asp1756=) rs377387902 0.00009
NM_001365276.2(TNXB):c.7685G>A (p.Arg2562Gln) rs200233352 0.00009
NM_001365276.2(TNXB):c.7889G>A (p.Arg2630His) rs374865424 0.00009
NM_001365276.2(TNXB):c.9467C>T (p.Pro3156Leu) rs200111122 0.00008
NM_001365276.2(TNXB):c.7296C>T (p.Thr2432=) rs753041189 0.00007
NM_001365276.2(TNXB):c.9308C>T (p.Ala3103Val) rs200191925 0.00007
NM_001365276.2(TNXB):c.147G>A (p.Gly49=) rs370126465 0.00006
NM_001365276.2(TNXB):c.2852C>T (p.Ala951Val) rs560124416 0.00006
NM_001365276.2(TNXB):c.3427G>A (p.Val1143Met) rs965570472 0.00006
NM_001365276.2(TNXB):c.5186C>T (p.Thr1729Ile) rs780774341 0.00006
NM_001365276.2(TNXB):c.5780T>C (p.Ile1927Thr) rs751320202 0.00006
NM_001365276.2(TNXB):c.6362G>A (p.Arg2121His) rs778533848 0.00006
NM_001365276.2(TNXB):c.4649G>A (p.Arg1550His) rs763075781 0.00005
NM_001365276.2(TNXB):c.4866C>T (p.Pro1622=) rs571254395 0.00005
NM_001365276.2(TNXB):c.7513G>A (p.Glu2505Lys) rs61731831 0.00005
NM_001365276.2(TNXB):c.8393G>A (p.Arg2798His) rs372230994 0.00005
NM_001365276.2(TNXB):c.9488C>G (p.Ala3163Gly) rs561810058 0.00005
NM_001365276.2(TNXB):c.9790C>T (p.Arg3264Cys) rs535345246 0.00005
NM_001365276.2(TNXB):c.2312C>G (p.Pro771Arg) rs199705832 0.00004
NM_001365276.2(TNXB):c.5285G>A (p.Arg1762Gln) rs547889326 0.00004
NM_001365276.2(TNXB):c.8353G>A (p.Glu2785Lys) rs771584531 0.00004
NM_001365276.2(TNXB):c.1252C>T (p.Arg418Cys) rs570402166 0.00003
NM_001365276.2(TNXB):c.2882A>G (p.Gln961Arg) rs551174904 0.00003
NM_001365276.2(TNXB):c.5204G>A (p.Arg1735His) rs573721058 0.00003
NM_001365276.2(TNXB):c.6208G>A (p.Val2070Ile) rs374970674 0.00003
NM_001365276.2(TNXB):c.7310G>A (p.Arg2437His) rs757178741 0.00003
NM_001365276.2(TNXB):c.7457G>A (p.Arg2486Gln) rs201546972 0.00003
NM_001365276.2(TNXB):c.8301C>T (p.Thr2767=) rs760906844 0.00003
NM_001365276.2(TNXB):c.9242T>C (p.Met3081Thr) rs774375168 0.00003
NM_001365276.2(TNXB):c.10356G>A (p.Leu3452=) rs764965013 0.00002
NM_001365276.2(TNXB):c.2461C>T (p.Arg821Ter) rs749890642 0.00002
NM_001365276.2(TNXB):c.3637G>A (p.Val1213Ile) rs774582576 0.00002
NM_001365276.2(TNXB):c.4360G>A (p.Ala1454Thr) rs374243353 0.00002
NM_001365276.2(TNXB):c.5942C>T (p.Thr1981Ile) rs1230512934 0.00002
NM_001365276.2(TNXB):c.6293dup (p.Glu2100fs) rs764867655 0.00002
NM_001365276.2(TNXB):c.7774G>A (p.Gly2592Ser) rs767643312 0.00002
NM_001365276.2(TNXB):c.8666G>A (p.Arg2889Gln) rs768863607 0.00002
NM_001365276.2(TNXB):c.9080A>G (p.Gln3027Arg) rs767216957 0.00002
NM_001365276.2(TNXB):c.9379A>G (p.Asn3127Asp) rs763951482 0.00002
NM_001365276.2(TNXB):c.9745G>A (p.Val3249Met) rs376344484 0.00002
NM_001365276.2(TNXB):c.10499G>A (p.Arg3500His) rs767560143 0.00001
NM_001365276.2(TNXB):c.1248C>A (p.Asp416Glu) rs775030992 0.00001
NM_001365276.2(TNXB):c.1290C>T (p.Cys430=) rs1331733789 0.00001
NM_001365276.2(TNXB):c.3034G>A (p.Val1012Ile) rs751045102 0.00001
NM_001365276.2(TNXB):c.4244C>T (p.Ala1415Val) rs770309992 0.00001
NM_001365276.2(TNXB):c.5603C>T (p.Thr1868Met) rs1188559992 0.00001
NM_001365276.2(TNXB):c.680G>A (p.Arg227His) rs750943669 0.00001
NM_001365276.2(TNXB):c.7327G>A (p.Val2443Met) rs201904621 0.00001
NM_001365276.2(TNXB):c.7783G>A (p.Glu2595Lys) rs374803743 0.00001
NM_001365276.2(TNXB):c.7826-1G>C rs200357005 0.00001
NM_001365276.2(TNXB):c.9271C>G (p.Leu3091Val) rs748558173 0.00001
NM_001365276.2(TNXB):c.9770C>T (p.Thr3257Ile) rs587777683 0.00001
NM_001365276.2(TNXB):c.9988C>A (p.Leu3330Ile) rs769294568 0.00001
NM_001365276.2(TNXB):c.10004dup (p.Asn3335fs) rs779059111
NM_001365276.2(TNXB):c.10199C>T (p.Pro3400Leu) rs777685355
NM_001365276.2(TNXB):c.1259T>C (p.Val420Ala) rs200226242
NM_001365276.2(TNXB):c.1878del (p.His626fs) rs1554334255
NM_001365276.2(TNXB):c.1948C>G (p.Arg650Gly) rs773316282
NM_001365276.2(TNXB):c.3290_3291del (p.Lys1097fs) rs764070148
NM_001365276.2(TNXB):c.3758C>A (p.Pro1253His) rs188789382
NM_001365276.2(TNXB):c.3763C>G (p.Arg1255Gly) rs376472382
NM_001365276.2(TNXB):c.4010G>A (p.Arg1337His) rs61735731
NM_001365276.2(TNXB):c.4573C>T (p.Arg1525Ter) rs779751914
NM_001365276.2(TNXB):c.5442C>G (p.Asp1814Glu) rs181025235
NM_001365276.2(TNXB):c.5625G>T (p.Pro1875=) rs376314262
NM_001365276.2(TNXB):c.6277G>C (p.Ala2093Pro) rs768829550
NM_001365276.2(TNXB):c.6550G>A (p.Glu2184Lys) rs754026612
NM_001365276.2(TNXB):c.6973G>A (p.Val2325Ile) rs140304758
NM_001365276.2(TNXB):c.7395C>T (p.Thr2465=) rs759303131
NM_001365276.2(TNXB):c.7399G>A (p.Gly2467Arg) rs765865300
NM_001365276.2(TNXB):c.7493-4del rs1352801514
NM_001365276.2(TNXB):c.7534C>G (p.Pro2512Ala) rs775958640
NM_001365276.2(TNXB):c.7620T>C (p.Leu2540=) rs547463127
NM_001365276.2(TNXB):c.8542G>C (p.Gly2848Arg) rs61745355
NM_001365276.2(TNXB):c.9044A>G (p.Lys3015Arg) rs1777360602
NM_001365276.2(TNXB):c.9195G>A (p.Glu3065=) rs201944713
NM_001365276.2(TNXB):c.935C>T (p.Pro312Leu) rs768599858

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