ClinVar Miner

Variants in gene TP53 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status: Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 73
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HGVS dbSNP
NM_000546.5(TP53):c.*1175A>C rs78378222
NM_000546.5(TP53):c.*6T>A rs369567704
NM_000546.5(TP53):c.100C>A (p.Pro34Thr) rs786201968
NM_000546.5(TP53):c.1015G>A (p.Glu339Lys) rs17882252
NM_000546.5(TP53):c.1015G>C (p.Glu339Gln) rs17882252
NM_000546.5(TP53):c.105G>C (p.Leu35Phe) rs121912661
NM_000546.5(TP53):c.1079G>C (p.Gly360Ala) rs35993958
NM_000546.5(TP53):c.1079G>T (p.Gly360Val) rs35993958
NM_000546.5(TP53):c.107C>A (p.Pro36Gln) rs587781866
NM_000546.5(TP53):c.1100+8A>G rs878854062
NM_000546.5(TP53):c.1120G>A (p.Gly374Ser) rs587781858
NM_000546.5(TP53):c.1120G>C (p.Gly374Arg) rs587781858
NM_000546.5(TP53):c.1135C>A (p.Arg379Ser) rs749061599
NM_000546.5(TP53):c.144C>A (p.Asp48Glu) rs587781460
NM_000546.5(TP53):c.145G>A (p.Asp49Asn) rs587780728
NM_000546.5(TP53):c.145G>C (p.Asp49His) rs587780728
NM_000546.5(TP53):c.149T>C (p.Ile50Thr) rs370502517
NM_000546.5(TP53):c.188C>T (p.Ala63Val) rs372201428
NM_000546.5(TP53):c.214C>A (p.Pro72Thr) rs587782769
NM_000546.5(TP53):c.21T>A (p.Asp7Glu) rs587781277
NM_000546.5(TP53):c.245C>T (p.Pro82Leu) rs534447939
NM_000546.5(TP53):c.248C>T (p.Ala83Val) rs201717599
NM_000546.5(TP53):c.250G>A (p.Ala84Thr) rs587781307
NM_000546.5(TP53):c.28G>C (p.Val10Leu) rs535274413
NM_000546.5(TP53):c.31G>A (p.Glu11Lys) rs201382018
NM_000546.5(TP53):c.385G>A (p.Ala129Thr) rs1438095083
NM_000546.5(TP53):c.464C>G (p.Thr155Ser) rs786202752
NM_000546.5(TP53):c.466C>T (p.Arg156Cys) rs563378859
NM_000546.5(TP53):c.509C>T (p.Thr170Met) rs779000871
NM_000546.5(TP53):c.554G>A (p.Ser185Asn) rs150607408
NM_000546.5(TP53):c.559+8G>A rs775915220
NM_000546.5(TP53):c.566C>T (p.Ala189Val) rs121912665
NM_000546.5(TP53):c.604C>G (p.Arg202Gly) rs587780072
NM_000546.5(TP53):c.604C>T (p.Arg202Cys) rs587780072
NM_000546.5(TP53):c.605G>A (p.Arg202His) rs587778719
NM_000546.5(TP53):c.663G>A (p.Glu221=) rs1060504161
NM_000546.5(TP53):c.665C>T (p.Pro222Leu) rs146340390
NM_000546.5(TP53):c.672+9T>C rs1057521030
NM_000546.5(TP53):c.704A>G (p.Asn235Ser) rs144340710
NM_000546.5(TP53):c.74+9A>C rs1057517593
NM_000546.5(TP53):c.782+12C>T rs17881780
NM_000546.5(TP53):c.787A>G (p.Asn263Asp) rs72661119
NM_000546.5(TP53):c.868C>T (p.Arg290Cys) rs770374782
NM_000546.5(TP53):c.884C>T (p.Pro295Leu) rs751713111
NM_000546.5(TP53):c.892G>A (p.Glu298Lys) rs201744589
NM_000546.5(TP53):c.907A>G (p.Ser303Gly) rs587782391
NM_000546.5(TP53):c.917G>A (p.Arg306Gln) rs1048095040
NM_000546.5(TP53):c.919+3A>G rs876659784
NM_000546.5(TP53):c.920-5C>T rs34361146
NM_000546.5(TP53):c.943T>A (p.Ser315Thr) rs762620193
NM_000546.5(TP53):c.949C>A (p.Gln317Lys) rs764735889
NM_000546.5(TP53):c.97-9C>T rs202217267
NM_000546.5(TP53):c.974G>A (p.Gly325Glu) rs121912659
NM_000546.5(TP53):c.998G>A (p.Arg333His) rs573154688
NM_000546.6(TP53):c.1093C>T (p.His365Tyr) rs267605075
NM_000546.6(TP53):c.1163A>C (p.Glu388Ala) rs587781736
NM_000546.6(TP53):c.140C>G (p.Pro47Arg) rs1597375038
NM_000546.6(TP53):c.221C>T (p.Ala74Val) rs587781832
NM_000546.6(TP53):c.28G>A (p.Val10Ile) rs535274413
NM_000546.6(TP53):c.31G>C (p.Glu11Gln) rs201382018
NM_000546.6(TP53):c.329G>A (p.Arg110His) rs11540654
NM_000546.6(TP53):c.467G>A (p.Arg156His) rs371524413
NM_000546.6(TP53):c.642T>G (p.His214Gln) rs587781386
NM_000546.6(TP53):c.66A>G (p.Leu22=) rs748527030
NM_000546.6(TP53):c.847C>T (p.Arg283Cys) rs149633775
NM_000546.6(TP53):c.869G>A (p.Arg290His) rs55819519
NM_000546.6(TP53):c.877G>T (p.Gly293Trp) rs587780076
NM_000546.6(TP53):c.886C>T (p.His296Tyr) rs672601296
NM_000546.6(TP53):c.91G>A (p.Val31Ile) rs201753350
NM_000546.6(TP53):c.935C>G (p.Thr312Ser) rs145151284
NM_000546.6(TP53):c.997C>T (p.Arg333Cys) rs769934890
NM_001126112.2(TP53):c.214_215delinsTG (p.Pro72Cys) rs730882014
NM_001126112.2(TP53):c.376-2dup rs751253294

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