ClinVar Miner

Variants in gene TP63 with conflicting interpretations "uncertain significance" and "likely benign"

Submission 1 (uncertain significance) minimum review status: Submission 1 (uncertain significance) method:
Submission 2 (likely benign) minimum review status: Submission 2 (likely benign) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 11
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HGVS dbSNP gnomAD frequency
NM_003722.5(TP63):c.678C>T (p.Arg226=) rs61732782 0.00034
NM_003722.5(TP63):c.1827A>G (p.Glu609=) rs147538847 0.00031
NM_003722.5(TP63):c.504C>T (p.Asn168=) rs141278696 0.00021
NM_003722.5(TP63):c.992+10G>A rs373106660 0.00016
NM_003722.5(TP63):c.374A>C (p.Gln125Pro) rs982556895 0.00013
NM_003722.5(TP63):c.1459C>T (p.Arg487Cys) rs777306829 0.00009
NM_003722.5(TP63):c.992+9C>T rs369838833 0.00005
NM_003722.5(TP63):c.688G>C (p.Val230Leu) rs201466089 0.00004
NM_003722.5(TP63):c.1761G>A (p.Leu587=) rs573105911 0.00002
NM_003722.5(TP63):c.1644C>T (p.Ser548=) rs763019843 0.00001
NM_003722.5(TP63):c.435G>C (p.Ala145=) rs546908184

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