ClinVar Miner

Variants in gene TPM1 with conflicting interpretations "benign" and "likely benign"

Submission 1 (benign) minimum review status: Submission 1 (benign) method:
Submission 2 (likely benign) minimum review status: Submission 2 (likely benign) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 32
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001018005.2(TPM1):c.453C>A (p.Ala151=) rs1071646 0.64628
NM_001018005.2(TPM1):c.486T>C (p.Tyr162=) rs11558747 0.05001
NM_001018005.2(TPM1):c.*148G>T rs7668 0.03733
NM_001018005.2(TPM1):c.851+99dup rs201411148 0.00955
NM_001018005.2(TPM1):c.639+22G>C rs28730802 0.00782
NM_001018020.2(TPM1):c.*31G>A rs11558748 0.00598
NM_001018005.2(TPM1):c.*76A>G rs140658011 0.00339
NM_001018005.2(TPM1):c.180C>T (p.Tyr60=) rs17850194 0.00273
NM_001018005.1(TPM1):c.-206G>A rs17525848 0.00111
NM_001018005.2(TPM1):c.115-262C>T rs74573041 0.00079
NM_001018005.2(TPM1):c.*68A>G rs374459540 0.00054
NM_001018004.2(TPM1):c.775A>G (p.Lys259Glu) rs144045691 0.00052
NM_001018005.2(TPM1):c.639+21G>C rs199989220 0.00041
NM_001018005.2(TPM1):c.177A>G (p.Lys59=) rs149346709 0.00031
NM_001018005.2(TPM1):c.375-5T>C rs377061868 0.00029
NM_001018005.2(TPM1):c.563+313A>G rs144700226 0.00029
NM_001018005.2(TPM1):c.115-214C>G rs947201175 0.00021
NM_001018005.2(TPM1):c.115-316G>A rs397516491 0.00015
NM_001018005.2(TPM1):c.114+14C>T rs576659891 0.00014
NM_001018005.2(TPM1):c.726G>A (p.Ala242=) rs200484871 0.00011
NM_001018005.2(TPM1):c.522C>T (p.Ser174=) rs200173919 0.00010
NM_001018005.2(TPM1):c.27G>A (p.Gln9=) rs397516365 0.00006
NM_001018005.2(TPM1):c.493-18T>G rs377726678 0.00006
NM_001018005.2(TPM1):c.241-8C>T rs765893032 0.00003
NM_001018005.2(TPM1):c.375-3C>T rs202228866 0.00003
NM_001018005.2(TPM1):c.663T>C (p.Tyr221=) rs774859181 0.00002
NM_001018005.1(TPM1):c.-186G>A rs541046450
NM_001018005.2(TPM1):c.115-277G>A rs1312883932
NM_001018005.2(TPM1):c.45G>A (p.Lys15=) rs199476301
NM_001018005.2(TPM1):c.61C>A (p.Arg21=) rs1437698471
NM_001018005.2(TPM1):c.639+13del rs397516488
NM_001018005.2(TPM1):c.87G>A (p.Lys29=) rs530234301

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.