ClinVar Miner

Variants in gene TRPM4 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
429 34 0 18 25 0 1 39

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic uncertain significance likely benign benign
pathogenic 0 1 1 0
uncertain significance 1 0 20 8
likely benign 1 20 0 18
benign 0 8 18 0

All variants with conflicting interpretations #

Total variants: 39
Download table as spreadsheet
NM_017636.4(TRPM4):c.1242T>C (p.Phe414=) rs200633475
NM_017636.4(TRPM4):c.1368C>G (p.Thr456=) rs56118173
NM_017636.4(TRPM4):c.1575G>A (p.Trp525Ter) rs71352737
NM_017636.4(TRPM4):c.1682A>C (p.Asp561Ala) rs56355369
NM_017636.4(TRPM4):c.1874-9C>T rs199805560
NM_017636.4(TRPM4):c.2133-9C>G rs530013543
NM_017636.4(TRPM4):c.2209G>A (p.Gly737Arg) rs145847114
NM_017636.4(TRPM4):c.2231A>T (p.Lys744Met) rs569301210
NM_017636.4(TRPM4):c.2254C>T (p.Gln752Ter) rs769917929
NM_017636.4(TRPM4):c.2283_2294del (p.759_762CGGR[1]) rs113100797
NM_017636.4(TRPM4):c.2531G>A (p.Gly844Asp) rs200038418
NM_017636.4(TRPM4):c.2561A>G (p.Gln854Arg) rs172155862
NM_017636.4(TRPM4):c.2619C>T (p.Thr873=) rs144544237
NM_017636.4(TRPM4):c.2674C>T (p.Arg892Cys) rs147854826
NM_017636.4(TRPM4):c.2740A>T (p.Lys914Ter) rs140799936
NM_017636.4(TRPM4):c.2779-5C>T rs374639233
NM_017636.4(TRPM4):c.286C>T (p.Arg96Ter) rs148855956
NM_017636.4(TRPM4):c.2934T>C (p.Ile978=) rs35516880
NM_017636.4(TRPM4):c.301G>A (p.Ala101Thr) rs113984787
NM_017636.4(TRPM4):c.306T>G (p.Val102=) rs111783027
NM_017636.4(TRPM4):c.3082C>T (p.Leu1028=) rs79286201
NM_017636.4(TRPM4):c.308A>G (p.Tyr103Cys) rs144781529
NM_017636.4(TRPM4):c.322C>T (p.Arg108Cys) rs115335683
NM_017636.4(TRPM4):c.3329-8C>G rs369748756
NM_017636.4(TRPM4):c.3377C>G (p.Ser1126Trp) rs567938424
NM_017636.4(TRPM4):c.3427A>G (p.Ser1143Gly) rs138603244
NM_017636.4(TRPM4):c.3450C>T (p.Arg1150=) rs763372824
NM_017636.4(TRPM4):c.3489A>G (p.Gly1163=) rs760190293
NM_017636.4(TRPM4):c.3611C>T (p.Pro1204Leu) rs150391806
NM_017636.4(TRPM4):c.448+6C>T rs78051297
NM_017636.4(TRPM4):c.449-10G>A rs78444754
NM_017636.4(TRPM4):c.566C>T (p.Ala189Val) rs145501662
NM_017636.4(TRPM4):c.618G>A (p.Ser206=) rs142788545
NM_017636.4(TRPM4):c.657C>T (p.Asp219=) rs373953725
NM_017636.4(TRPM4):c.748C>T (p.Arg250Cys) rs144208673
NM_017636.4(TRPM4):c.755G>A (p.Arg252His) rs146564314
NM_017636.4(TRPM4):c.783G>A (p.Lys261=) rs111930830
NM_017636.4(TRPM4):c.870C>T (p.Asn290=) rs141997826
NM_017636.4(TRPM4):c.988G>A (p.Glu330Lys) rs145771389

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