ClinVar Miner

Variants in gene TRPM4 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
242 31 0 25 25 1 4 48

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign association drug response
pathogenic 0 0 1 1 0 0 0
likely pathogenic 0 0 1 0 1 0 0
uncertain significance 2 2 0 24 6 1 1
likely benign 1 0 23 0 25 0 0
benign 0 1 5 25 0 0 0

All variants with conflicting interpretations #

Total variants: 48
Download table as spreadsheet
NM_017636.4(TRPM4):c.-12G>A rs3760663
NM_017636.4(TRPM4):c.1041G>T (p.Leu347=) rs61732831
NM_017636.4(TRPM4):c.1082T>G (p.Leu361Arg) rs148763371
NM_017636.4(TRPM4):c.1119C>A (p.Phe373Leu) rs141531245
NM_017636.4(TRPM4):c.1150+1G>A rs200132598
NM_017636.4(TRPM4):c.1164G>A (p.Ser388=) rs144201184
NM_017636.4(TRPM4):c.1242T>C (p.Phe414=) rs200633475
NM_017636.4(TRPM4):c.1368C>G (p.Thr456=) rs56118173
NM_017636.4(TRPM4):c.1459_1494del (p.Lys487_Leu498del) rs878855029
NM_017636.4(TRPM4):c.1575G>A (p.Trp525Ter) rs71352737
NM_017636.4(TRPM4):c.1682A>C (p.Asp561Ala) rs56355369
NM_017636.4(TRPM4):c.2085C>T (p.Leu695=) rs781191851
NM_017636.4(TRPM4):c.2133-9C>G rs530013543
NM_017636.4(TRPM4):c.2210+11C>G rs1175796
NM_017636.4(TRPM4):c.2231A>T (p.Lys744Met) rs569301210
NM_017636.4(TRPM4):c.2254C>T (p.Gln752Ter) rs769917929
NM_017636.4(TRPM4):c.2283_2294del (p.759_762CGGR[1]) rs113100797
NM_017636.4(TRPM4):c.2380C>T (p.Leu794=) rs3745301
NM_017636.4(TRPM4):c.24+6C>G rs767900879
NM_017636.4(TRPM4):c.249C>T (p.Ala83=) rs142270489
NM_017636.4(TRPM4):c.2531G>A (p.Gly844Asp) rs200038418
NM_017636.4(TRPM4):c.267+14C>G rs113040724
NM_017636.4(TRPM4):c.2674C>T (p.Arg892Cys) rs147854826
NM_017636.4(TRPM4):c.2740A>T (p.Lys914Ter) rs140799936
NM_017636.4(TRPM4):c.2779-5C>T rs374639233
NM_017636.4(TRPM4):c.286C>T (p.Arg96Ter) rs148855956
NM_017636.4(TRPM4):c.2934T>C (p.Ile978=) rs35516880
NM_017636.4(TRPM4):c.2982G>A (p.Ser994=) rs1175810
NM_017636.4(TRPM4):c.2987_3014del (p.Glu996fs) rs765535147
NM_017636.4(TRPM4):c.3024G>A (p.Ala1008=) rs35145363
NM_017636.4(TRPM4):c.3073G>A (p.Val1025Ile) rs186822052
NM_017636.4(TRPM4):c.3082C>T (p.Leu1028=) rs79286201
NM_017636.4(TRPM4):c.308A>G (p.Tyr103Cys) rs144781529
NM_017636.4(TRPM4):c.322C>T (p.Arg108Cys) rs115335683
NM_017636.4(TRPM4):c.3450C>T (p.Arg1150=) rs763372824
NM_017636.4(TRPM4):c.3611C>T (p.Pro1204Leu) rs150391806
NM_017636.4(TRPM4):c.375G>A (p.Ser125=) rs34333830
NM_017636.4(TRPM4):c.448+6C>T rs78051297
NM_017636.4(TRPM4):c.449-10G>A rs78444754
NM_017636.4(TRPM4):c.566C>T (p.Ala189Val) rs145501662
NM_017636.4(TRPM4):c.618G>A (p.Ser206=) rs142788545
NM_017636.4(TRPM4):c.748C>T (p.Arg250Cys) rs144208673
NM_017636.4(TRPM4):c.783G>A (p.Lys261=) rs111930830
NM_017636.4(TRPM4):c.870C>T (p.Asn290=) rs141997826
NM_017636.4(TRPM4):c.92+12G>A rs377431946
NM_017636.4(TRPM4):c.936G>A (p.Ala312=)
NM_017636.4(TRPM4):c.988G>A (p.Glu330Lys) rs145771389
Single allele

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