Variants in gene TSC1 with conflicting interpretations "pathogenic" and "likely pathogenic"

Submission 1 (pathogenic) minimum review status:		Submission 1 (pathogenic) method:
Submission 2 (likely pathogenic) minimum review status:		Submission 2 (likely pathogenic) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 21

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HGVS	dbSNP	gnomAD frequency
NM_000368.5(TSC1):c.1525C>T (p.Arg509Ter)	rs118203542
NM_000368.5(TSC1):c.1579C>T (p.Gln527Ter)	rs118203549
NM_000368.5(TSC1):c.1996A>T (p.Lys666Ter)	rs1845604585
NM_000368.5(TSC1):c.1998-2A>G	rs1057518217
NM_000368.5(TSC1):c.2208+2T>A	rs1064794132
NM_000368.5(TSC1):c.232G>T (p.Glu78Ter)	rs1588355838
NM_000368.5(TSC1):c.2626-1G>A	rs397514847
NM_000368.5(TSC1):c.2806C>T (p.Gln936Ter)	rs118203735
NM_000368.5(TSC1):c.2818C>T (p.Gln940Ter)	rs1588290078
NM_000368.5(TSC1):c.363+1G>T	rs118203372
NM_000368.5(TSC1):c.364-2A>G	rs1846685279
NM_000368.5(TSC1):c.508+2T>C	rs2132185885
NM_000368.5(TSC1):c.663+1G>A	rs118203419
NM_000368.5(TSC1):c.664-15A>G	rs118203422
NM_000368.5(TSC1):c.664-1G>A	rs118203423
NM_000368.5(TSC1):c.671T>G (p.Met224Arg)	rs118203426
NM_000368.5(TSC1):c.733C>T (p.Arg245Ter)	rs118203434
NM_000368.5(TSC1):c.737+3A>G	rs118203439
NM_000368.5(TSC1):c.737G>A (p.Arg246Lys)	rs118203436
NM_000368.5(TSC1):c.982C>T (p.Gln328Ter)	rs1554817388
Single allele

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