Variants in gene VCL with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status:		Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 41

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HGVS	dbSNP	gnomAD frequency
NM_014000.3(VCL):c.1555A>C (p.Ile519Leu)	rs141033098	0.00064
NM_014000.3(VCL):c.2521G>C (p.Asp841His)	rs150385900	0.00051
NM_014000.3(VCL):c.1297C>T (p.Arg433Cys)	rs139559937	0.00026
NM_014000.3(VCL):c.1294C>G (p.Leu432Val)	rs144146254	0.00025
NM_014000.3(VCL):c.787A>T (p.Thr263Ser)	rs142233726	0.00022
NM_014000.3(VCL):c.2427C>T (p.Ser809=)	rs183739128	0.00019
NM_014000.3(VCL):c.590C>T (p.Thr197Ile)	rs189242810	0.00019
NM_014000.3(VCL):c.1403C>T (p.Thr468Met)	rs147957747	0.00013
NM_014000.3(VCL):c.2796T>C (p.Asp932=)	rs140308982	0.00012
NM_014000.3(VCL):c.829C>A (p.Leu277Met)	rs71579353	0.00010
NM_014000.3(VCL):c.3066C>T (p.Ile1022=)	rs138619320	0.00009
NM_014000.3(VCL):c.2802C>T (p.Ala934=)	rs372381809	0.00007
NM_014000.3(VCL):c.2468G>A (p.Arg823Gln)	rs759202535	0.00006
NM_014000.3(VCL):c.2748G>A (p.Pro916=)	rs761794669	0.00006
NM_014000.3(VCL):c.404T>C (p.Ile135Thr)	rs373744314	0.00006
NM_014000.3(VCL):c.1177-14G>A	rs778137720	0.00004
NM_014000.3(VCL):c.1534C>T (p.Arg512Cys)	rs781079975	0.00004
NM_014000.3(VCL):c.1607C>A (p.Pro536His)	rs200624351	0.00004
NM_014000.3(VCL):c.2472C>G (p.Ile824Met)	rs140381835	0.00004
NM_014000.3(VCL):c.2652G>A (p.Glu884=)	rs371187988	0.00004
NM_014000.3(VCL):c.2746-8C>T	rs532645343	0.00004
NM_014000.3(VCL):c.2875A>C (p.Asn959His)	rs758969419	0.00003
NM_014000.3(VCL):c.1404G>A (p.Thr468=)	rs772104870	0.00002
NM_014000.3(VCL):c.1756C>T (p.Arg586Trp)	rs770778046	0.00002
NM_014000.3(VCL):c.2746-14C>T	rs367598954	0.00002
NM_014000.3(VCL):c.783+5G>A	rs767694507	0.00002
NM_014000.3(VCL):c.808T>C (p.Leu270=)	rs727505339	0.00002
NM_014000.3(VCL):c.1433A>G (p.Asn478Ser)	rs763235691	0.00001
NM_014000.3(VCL):c.1543+8C>G	rs886047218	0.00001
NM_014000.3(VCL):c.2852C>G (p.Pro951Arg)	rs368570586	0.00001
NM_014000.3(VCL):c.2924G>A (p.Arg975Gln)	rs767325003	0.00001
NM_014000.3(VCL):c.3186G>A (p.Gln1062=)	rs761534024	0.00001
NM_014000.3(VCL):c.3259-5T>C	rs1057523095	0.00001
NM_014000.3(VCL):c.854G>A (p.Arg285His)	rs397517246	0.00001
NM_014000.3(VCL):c.1157A>G (p.Lys386Arg)	rs200342284
NM_014000.3(VCL):c.1296_1297inv (p.Arg433Cys)
NM_014000.3(VCL):c.1704G>A (p.Gln568=)	rs1839959715
NM_014000.3(VCL):c.1973T>C (p.Val658Ala)	rs372691803
NM_014000.3(VCL):c.2862_2864del (p.Leu955del)	rs397517237
NM_014000.3(VCL):c.622+4C>G	rs201020802
NM_014000.3(VCL):c.789T>C (p.Thr263=)	rs538002543

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