ClinVar Miner

Variants in gene WDR35 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
67 96 5 13 5 0 3 22

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 5 6 3 0 0
likely pathogenic 6 0 1 0 0
uncertain significance 3 1 0 3 3
likely benign 0 0 3 0 7
benign 0 0 3 7 0

All variants with conflicting interpretations #

Total variants: 22
Download table as spreadsheet
NM_001006657.2(WDR35):c.1058G>C (p.Arg353Pro) rs76623454
NM_001006657.2(WDR35):c.1288+1G>A rs371669862
NM_001006657.2(WDR35):c.1501del (p.Gln501fs) rs886044119
NM_001006657.2(WDR35):c.1592T>C (p.Leu531Pro) rs397515533
NM_001006657.2(WDR35):c.1788C>T (p.Val596=) rs146130105
NM_001006657.2(WDR35):c.1877A>G (p.Glu626Gly) rs267607174
NM_001006657.2(WDR35):c.1922T>G (p.Leu641Ter) rs199952377
NM_001006657.2(WDR35):c.206G>A (p.Gly69Asp) rs765513105
NM_001006657.2(WDR35):c.2099G>A (p.Arg700His) rs74470618
NM_001006657.2(WDR35):c.2182A>G (p.Ile728Val) rs144493712
NM_001006657.2(WDR35):c.2599G>T (p.Val867Phe) rs149667250
NM_001006657.2(WDR35):c.2623G>A (p.Ala875Thr) rs267607175
NM_001006657.2(WDR35):c.2632G>A (p.Ala878Thr) rs2293669
NM_001006657.2(WDR35):c.2891del (p.Pro964fs) rs397515334
NM_001006657.2(WDR35):c.3091C>T (p.His1031Tyr) rs1553316264
NM_001006657.2(WDR35):c.3154+12A>C rs28502265
NM_001006657.2(WDR35):c.3154+3G>A rs200042577
NM_001006657.2(WDR35):c.3203A>G (p.Tyr1068Cys) rs541910371
NM_001006657.2(WDR35):c.355C>T (p.Arg119Cys) rs140308808
NM_001006657.2(WDR35):c.549C>T (p.Tyr183=) rs34169020
NM_001006657.2(WDR35):c.770T>C (p.Val257Ala) rs142955097
NM_001006657.2(WDR35):c.932G>T (p.Trp311Leu) rs200649783

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