ClinVar Miner

Variants in gene WDR35 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
266 9 1 7 5 0 4 16

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 1 6 2 0 0
likely pathogenic 6 0 2 0 0
uncertain significance 2 2 0 4 1
likely benign 0 0 4 0 1
benign 0 0 1 1 0

All variants with conflicting interpretations #

Total variants: 16
Download table as spreadsheet
NM_020779.4(WDR35):c.1183A>T (p.Asn395Tyr) rs143343508
NM_020779.4(WDR35):c.1227A>G (p.Thr409=) rs148828104
NM_020779.4(WDR35):c.1248T>G (p.Ile416Met) rs144701688
NM_020779.4(WDR35):c.1400+3A>G rs776631281
NM_020779.4(WDR35):c.1468del (p.Gln490fs) rs886044119
NM_020779.4(WDR35):c.1844A>G (p.Glu615Gly) rs267607174
NM_020779.4(WDR35):c.1889T>G (p.Leu630Ter) rs199952377
NM_020779.4(WDR35):c.2066G>A (p.Arg689His) rs74470618
NM_020779.4(WDR35):c.206G>A (p.Gly69Asp) rs765513105
NM_020779.4(WDR35):c.2489A>T (p.Asp830Val) rs1553316926
NM_020779.4(WDR35):c.2678T>C (p.Leu893Ser) rs151047156
NM_020779.4(WDR35):c.3058C>T (p.His1020Tyr) rs1553316264
NM_020779.4(WDR35):c.3170A>G (p.Tyr1057Cys) rs541910371
NM_020779.4(WDR35):c.355C>T (p.Arg119Cys) rs140308808
NM_020779.4(WDR35):c.770T>C (p.Val257Ala) rs142955097
NM_020779.4(WDR35):c.932G>T (p.Trp311Leu) rs200649783

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