Variants in gene WNK1 with conflicting interpretations "likely benign" and "uncertain significance"

Submission 1 (likely benign) minimum review status:		Submission 1 (likely benign) method:
Submission 2 (uncertain significance) minimum review status:		Submission 2 (uncertain significance) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 42

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HGVS	dbSNP	gnomAD frequency
NM_213655.5(WNK1):c.2201C>T (p.Pro734Leu)	rs564717613	0.00161
NM_018979.4(WNK1):c.1074C>T (p.Thr358=)	rs72648621	0.00160
NM_018979.4(WNK1):c.6150T>C (p.Leu2050=)	rs151331381	0.00157
NM_018979.4(WNK1):c.5638G>A (p.Ala1880Thr)	rs72650763	0.00097
NM_018979.4(WNK1):c.2206A>G (p.Ile736Val)	rs147099510	0.00096
NM_018979.4(WNK1):c.1855A>G (p.Thr619Ala)	rs149388376	0.00086
NM_018979.4(WNK1):c.7021G>A (p.Gly2341Ser)	rs146042595	0.00062
NM_213655.5(WNK1):c.2360G>A (p.Arg787Gln)	rs550716144	0.00061
NM_018979.4(WNK1):c.578C>A (p.Pro193Gln)	rs72647372	0.00058
NM_213655.5(WNK1):c.2995C>G (p.Leu999Val)	rs72649856	0.00046
NM_018979.4(WNK1):c.3578G>A (p.Ser1193Asn)	rs72650720	0.00045
NM_018979.4(WNK1):c.5050A>G (p.Ile1684Val)	rs770568108	0.00039
NM_018979.4(WNK1):c.5741T>C (p.Ile1914Thr)	rs184764148	0.00032
NM_018979.4(WNK1):c.5720C>T (p.Pro1907Leu)	rs200979623	0.00026
NM_018979.4(WNK1):c.5869C>T (p.Arg1957Cys)	rs201766777	0.00026
NM_213655.5(WNK1):c.2939G>T (p.Ser980Ile)	rs372091476	0.00026
NM_213655.5(WNK1):c.3371G>A (p.Gly1124Glu)	rs201042606	0.00024
NM_018979.4(WNK1):c.865T>C (p.Ser289Pro)	rs200234585	0.00022
NM_018979.4(WNK1):c.5851A>G (p.Thr1951Ala)	rs72650764	0.00020
NM_018979.4(WNK1):c.1834G>A (p.Gly612Ser)	rs146450828	0.00014
NM_018979.4(WNK1):c.3188C>T (p.Thr1063Ile)	rs201379287	0.00013
NM_018979.4(WNK1):c.4788A>G (p.Gln1596=)	rs371448826	0.00012
NM_213655.5(WNK1):c.2533C>T (p.Arg845Cys)	rs200794710	0.00011
NM_213655.5(WNK1):c.2605C>A (p.Leu869Ile)	rs377073379	0.00011
NM_018979.4(WNK1):c.5714T>A (p.Val1905Glu)	rs759895083	0.00009
NM_213655.5(WNK1):c.3107C>T (p.Ala1036Val)	rs187534119	0.00009
NM_018979.4(WNK1):c.4130T>A (p.Val1377Glu)	rs574069625	0.00008
NM_018979.4(WNK1):c.5144A>G (p.Asn1715Ser)	rs756614581	0.00006
NM_018979.4(WNK1):c.5734A>C (p.Ile1912Leu)	rs201995891	0.00006
NM_018979.4(WNK1):c.7138C>T (p.Arg2380Trp)	rs56262445	0.00005
NM_018979.4(WNK1):c.2266C>G (p.Gln756Glu)	rs768622577	0.00004
NM_018979.4(WNK1):c.4135A>G (p.Thr1379Ala)	rs758763241	0.00004
NM_018979.4(WNK1):c.3935G>A (p.Arg1312His)	rs375565845	0.00003
NM_018979.4(WNK1):c.5325C>T (p.Ser1775=)	rs373370309	0.00002
NM_213655.5(WNK1):c.2233G>A (p.Ala745Thr)	rs763686798	0.00002
NM_018979.4(WNK1):c.131C>T (p.Ala44Val)	rs754447060	0.00001
NM_018979.4(WNK1):c.397G>A (p.Val133Ile)	rs753342253	0.00001
NM_018979.4(WNK1):c.5312G>T (p.Gly1771Val)	rs770566791	0.00001
NM_018979.4(WNK1):c.5442G>A (p.Ala1814=)	rs557930357	0.00001
NM_018979.4(WNK1):c.5584-5A>G	rs771801197	0.00001
NM_018979.4(WNK1):c.1269G>A (p.Ser423=)	rs955095527
NM_213655.5(WNK1):c.2172dup (p.Pro725fs)	rs910119961

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