Variants in gene WRN with conflicting interpretations "benign" and "likely benign"

Submission 1 (benign) minimum review status:		Submission 1 (benign) method:
Submission 2 (likely benign) minimum review status:		Submission 2 (likely benign) method:
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants with conflicting interpretations: 27

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HGVS	dbSNP	gnomAD frequency
NM_000553.6(WRN):c.3222G>T (p.Leu1074Phe)	rs1801195	0.46398
NM_000553.6(WRN):c.3138+7G>A	rs2737335	0.46283
NM_000553.6(WRN):c.2361G>T (p.Leu787=)	rs1800392	0.44630
NM_000553.6(WRN):c.3138+6C>T	rs3024239	0.39769
NM_000553.6(WRN):c.4083C>T (p.Ser1361=)	rs1801196	0.28751
NM_000553.6(WRN):c.4099T>C (p.Cys1367Arg)	rs1346044	0.22492
NM_000553.6(WRN):c.1577-3C>A	rs3087409	0.07869
NM_000553.6(WRN):c.340G>A (p.Val114Ile)	rs2230009	0.07797
NM_000553.6(WRN):c.1161G>A (p.Met387Ile)	rs1800391	0.06046
NM_000553.6(WRN):c.3236C>T (p.Ser1079Leu)	rs3087414	0.01577
NM_000553.6(WRN):c.2241T>G (p.Leu747=)	rs2230011	0.00921
NM_000553.6(WRN):c.1953C>T (p.Gly651=)	rs11574263	0.00627
NM_000553.6(WRN):c.1725T>C (p.Tyr575=)	rs13438802	0.00516
NM_000553.6(WRN):c.1788T>C (p.Ser596=)	rs13438803	0.00512
NM_000553.6(WRN):c.4015G>A (p.Val1339Ile)	rs11574395	0.00418
NM_000553.6(WRN):c.1577-17T>G	rs145080962	0.00363
NM_000553.6(WRN):c.95A>G (p.Lys32Arg)	rs34477820	0.00310
NM_000553.6(WRN):c.3785C>G (p.Thr1262Arg)	rs78488552	0.00276
NM_000553.6(WRN):c.970A>G (p.Thr324Ala)	rs1800390	0.00245
NM_000553.6(WRN):c.2983G>A (p.Ala995Thr)	rs140768346	0.00193
NM_000553.6(WRN):c.1149G>T (p.Leu383Phe)	rs4987238	0.00148
NM_000553.6(WRN):c.2500C>T (p.Arg834Cys)	rs3087425	0.00089
NM_000553.6(WRN):c.3237G>A (p.Ser1079=)	rs11574345	0.00069
NM_000553.6(WRN):c.3422C>T (p.Ser1141Leu)	rs139323683	0.00052
NM_000553.6(WRN):c.1882C>G (p.Leu628Val)	rs77969734	0.00050
NM_000553.6(WRN):c.1899-10G>T	rs748285435
NM_000553.6(WRN):c.1982-5del	rs397723919

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