ClinVar Miner

Variants in gene WRN with conflicting interpretations "benign" and "uncertain significance"

Submission 1 (benign) minimum review status: Submission 1 (benign) method:
Submission 2 (uncertain significance) minimum review status: Submission 2 (uncertain significance) method:
Gene type:
ClinVar version:
Total variants with conflicting interpretations: 14
Download table as spreadsheet
HGVS dbSNP
NM_000553.6(WRN):c.1149G>T (p.Leu383Phe) rs4987238
NM_000553.6(WRN):c.1530A>T (p.Glu510Asp) rs149565907
NM_000553.6(WRN):c.16T>C (p.Leu6=) rs202148988
NM_000553.6(WRN):c.1717A>G (p.Thr573Ala) rs150148567
NM_000553.6(WRN):c.1909C>T (p.Arg637Trp) rs148286708
NM_000553.6(WRN):c.2342C>T (p.Thr781Ile) rs17847568
NM_000553.6(WRN):c.2500C>T (p.Arg834Cys) rs3087425
NM_000553.6(WRN):c.2983G>A (p.Ala995Thr) rs140768346
NM_000553.6(WRN):c.355+4G>C rs145764920
NM_000553.6(WRN):c.3785C>G (p.Thr1262Arg) rs78488552
NM_000553.6(WRN):c.3875C>A (p.Ser1292Tyr) rs142614369
NM_000553.6(WRN):c.3900C>A (p.Pro1300=) rs138886038
NM_000553.6(WRN):c.4180A>G (p.Ile1394Val) rs545431480
NM_000553.6(WRN):c.95A>G (p.Lys32Arg) rs34477820

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.