ClinVar Miner

Variants in gene XRCC2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
240 51 0 7 9 0 4 18

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 2 0 0
likely pathogenic 1 0 3 0 0
uncertain significance 2 3 0 9 2
likely benign 0 0 9 0 6
benign 0 0 2 6 0

All variants with conflicting interpretations #

Total variants: 18
Download table as spreadsheet
NM_005431.2(XRCC2):c.122-3C>T rs730882046
NM_005431.2(XRCC2):c.190C>T (p.Arg64Ter) rs151110146
NM_005431.2(XRCC2):c.223G>C (p.Glu75Gln) rs1327414828
NM_005431.2(XRCC2):c.225A>G (p.Glu75=) rs751651780
NM_005431.2(XRCC2):c.282A>G (p.Thr94=) rs376598559
NM_005431.2(XRCC2):c.283A>G (p.Ile95Val) rs140214637
NM_005431.2(XRCC2):c.350dup (p.Leu117fs) rs764640893
NM_005431.2(XRCC2):c.354G>A (p.Val118=) rs558977371
NM_005431.2(XRCC2):c.378_381del (p.Leu126fs) rs763401560
NM_005431.2(XRCC2):c.40-10C>T rs3218472
NM_005431.2(XRCC2):c.477C>T (p.Arg159=) rs202226401
NM_005431.2(XRCC2):c.620A>G (p.Glu207Gly) rs61762969
NM_005431.2(XRCC2):c.643C>T (p.Arg215Ter) rs143153871
NM_005431.2(XRCC2):c.678T>C (p.Tyr226=) rs143357617
NM_005431.2(XRCC2):c.742C>G (p.Gln248Glu) rs190900560
NM_005431.2(XRCC2):c.808T>G (p.Phe270Val) rs145085742
NM_005431.2(XRCC2):c.842G>A (p.Ter281=) rs757510359
NM_005431.2(XRCC2):c.96del (p.Phe32fs) rs730882048

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