ClinVar Miner

Variants with conflicting interpretations "uncertain significance" from Sharing Clinical Reports Project (SCRP) and "likely benign" from any submitter

Minimum review status of the submission from Sharing Clinical Reports Project (SCRP): Collection method of the submission from Sharing Clinical Reports Project (SCRP):
Minimum review status of the other submission: Collection method of the other submission:
ClinVar version:
Total variants with conflicting interpretations: 51
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HGVS dbSNP gnomAD frequency
NM_000059.4(BRCA2):c.9634G>C (p.Gly3212Arg) rs55775473 0.00141
NM_000059.4(BRCA2):c.2138A>T (p.Gln713Leu) rs55816687 0.00138
NM_000059.4(BRCA2):c.8905G>A (p.Val2969Met) rs59004709 0.00019
NM_000059.4(BRCA2):c.1889C>T (p.Thr630Ile) rs80358479 0.00012
NM_007294.4(BRCA1):c.5158A>G (p.Thr1720Ala) rs56195342 0.00011
NM_000059.4(BRCA2):c.6338A>G (p.Asn2113Ser) rs80358874 0.00009
NM_000059.4(BRCA2):c.8215G>A (p.Val2739Ile) rs80359069 0.00009
NM_000059.4(BRCA2):c.1096T>G (p.Leu366Val) rs587779357 0.00006
NM_000059.4(BRCA2):c.8092G>A (p.Ala2698Thr) rs80359052 0.00005
NM_007294.4(BRCA1):c.199G>T (p.Asp67Tyr) rs80357102 0.00005
NM_000059.4(BRCA2):c.3581G>A (p.Gly1194Asp) rs28897721 0.00003
NM_000059.4(BRCA2):c.8134G>A (p.Asp2712Asn) rs80359056 0.00003
NM_000059.4(BRCA2):c.9253A>C (p.Thr3085Pro) rs397507423 0.00003
NM_000059.4(BRCA2):c.172G>A (p.Glu58Lys) rs397507603 0.00002
NM_000059.4(BRCA2):c.5113A>G (p.Ile1705Val) rs80358737 0.00002
NM_000059.4(BRCA2):c.7534C>T (p.Leu2512Phe) rs80358980 0.00002
NM_000059.4(BRCA2):c.8360G>A (p.Arg2787His) rs80359078 0.00002
NM_000059.4(BRCA2):c.1342C>T (p.Arg448Cys) rs80358422 0.00001
NM_000059.4(BRCA2):c.1550A>G (p.Asn517Ser) rs80358439 0.00001
NM_000059.4(BRCA2):c.2186T>C (p.Ile729Thr) rs431825296 0.00001
NM_000059.4(BRCA2):c.2755G>A (p.Glu919Lys) rs431825298 0.00001
NM_000059.4(BRCA2):c.3966C>G (p.Asn1322Lys) rs80358647 0.00001
NM_000059.4(BRCA2):c.489T>G (p.Ser163Arg) rs398122787 0.00001
NM_000059.4(BRCA2):c.5378A>G (p.Asn1793Ser) rs80358759 0.00001
NM_000059.4(BRCA2):c.67+4T>C rs373546450 0.00001
NM_000059.4(BRCA2):c.682-13A>G rs81002888 0.00001
NM_000059.4(BRCA2):c.7628A>G (p.Tyr2543Cys) rs431825354 0.00001
NM_000059.4(BRCA2):c.8351G>A (p.Arg2784Gln) rs80359076 0.00001
NM_007294.4(BRCA1):c.548-18T>G rs397507251 0.00001
NM_000059.4(BRCA2):c.1146A>T (p.Lys382Asn) rs431825280
NM_000059.4(BRCA2):c.1627C>A (p.His543Asn) rs80358446
NM_000059.4(BRCA2):c.2045T>C (p.Ile682Thr) rs398122739
NM_000059.4(BRCA2):c.2424A>G (p.Glu808=) rs55646808
NM_000059.4(BRCA2):c.3330A>G (p.Glu1110=) rs369294255
NM_000059.4(BRCA2):c.4054G>T (p.Asp1352Tyr) rs80358655
NM_000059.4(BRCA2):c.4391C>T (p.Ser1464Phe) rs587776464
NM_000059.4(BRCA2):c.517-12C>A rs398122795
NM_000059.4(BRCA2):c.6971A>G (p.His2324Arg) rs398122574
NM_000059.4(BRCA2):c.7008-5T>C rs397507380
NM_000059.4(BRCA2):c.7598C>G (p.Ser2533Cys) rs80358987
NM_000059.4(BRCA2):c.777A>G (p.Arg259=) rs431825356
NM_000059.4(BRCA2):c.8366A>G (p.Tyr2789Cys) rs398122603
NM_000059.4(BRCA2):c.9118-6C>T rs81002890
NM_000059.4(BRCA2):c.9257-8C>T rs11571819
NM_007294.4(BRCA1):c.124A>G (p.Ile42Val) rs80357163
NM_007294.4(BRCA1):c.135-15C>G rs397507185
NM_007294.4(BRCA1):c.216C>A (p.Ser72Arg) rs80356967
NM_007294.4(BRCA1):c.2917C>G (p.Leu973Val) rs80357080
NM_007294.4(BRCA1):c.2967T>A (p.Phe989Leu) rs876659270
NM_007294.4(BRCA1):c.4657T>A (p.Leu1553Met) rs80357431
NM_007294.4(BRCA1):c.5406A>C (p.Thr1802=) rs879255493

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