If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.
| Variants with only 1 submission per condition | Variants with at least 2 submissions on the same condition and no conflicts |
Variants with a synonymous conflict (e.g. benign vs non-pathogenic) |
Variants with a confidence conflict (e.g. benign vs likely benign) |
Variants with a benign or likely benign vs uncertain conflict |
Variants with a category conflict (e.g. benign vs affects) |
Variants with a clinically significant conflict (e.g. benign vs pathogenic) |
Variants with any conflict |
|---|---|---|---|---|---|---|---|
| 187 | 86 | 9 | 4 | 3 | 0 | 10 | 24 |
Significance breakdown #
In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.
| All submitters | |||||
|---|---|---|---|---|---|
| Richard Lifton Laboratory, |
pathogenic | likely pathogenic | uncertain significance | likely benign | |
| likely pathogenic | 4 | 1 | 10 | 0 | |
| uncertain significance | 0 | 9 | 8 | 3 | |
Submitter to submitter summary #
Total submitters: 14
| Submitter | Variants with only 1 submission per condition | Variants with at least 2 submissions on the same condition and no conflicts |
Variants with a synonymous conflict (e.g. benign vs non-pathogenic) |
Variants with a confidence conflict (e.g. benign vs likely benign) |
Variants with a benign or likely benign vs uncertain conflict |
Variants with a category conflict (e.g. benign vs affects) |
Variants with a clinically significant conflict (e.g. benign vs pathogenic) |
Variants with any conflict |
|---|---|---|---|---|---|---|---|---|
| Richard Lifton Laboratory, Yale University School of Medicine | 194 | 94 | 0 | 0 | 0 | 0 | 9 | 9 |
| Labcorp Genetics (formerly Invitae), Labcorp | 0 | 0 | 3 | 1 | 2 | 0 | 1 | 6 |
| GeneDx | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2 |
| Ambry Genetics | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 2 |
| OMIM | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
| Athena Diagnostics | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
| Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| Genome Diagnostics Laboratory, The Hospital for Sick Children | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
| ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| PreventionGenetics, part of Exact Sciences | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
| Mayo Clinic Laboratories, Mayo Clinic | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| Quest Diagnostics Nichols Institute San Juan Capistrano | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
| Database of Curated Mutations (DoCM) | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| Breakthrough Genomics, Breakthrough Genomics | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
All variants with conflicting interpretations #
Total variants: 24