Variants from International Pleuropulmonary Blastoma Registry,Children's Hospitals and Clinics of Minnesota with conflicting interpretations

Minimum review status of the submission from International Pleuropulmonary Blastoma Registry,Children's Hospitals and Clinics of Minnesota:		Collection method of the submission from International Pleuropulmonary Blastoma Registry,Children's Hospitals and Clinics of Minnesota:
Minimum review status of the other submission:		Collection method of the other submission:
Minimum conflict level: Report conflict between different conditions
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition	Variants with at least 2 submissions on the same condition and no conflicts	Variants with a synonymous conflict (e.g. benign vs non-pathogenic)	Variants with a confidence conflict (e.g. benign vs likely benign)	Variants with a benign or likely benign vs uncertain conflict	Variants with a category conflict (e.g. benign vs affects)	Variants with a clinically significant conflict (e.g. benign vs pathogenic)	Variants with any conflict
3	75	0	4	0	0	1	5

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

	All submitters
International Pleuropulmonary Blastoma Registry,Children's Hospitals and Clinics of Minnesota		likely pathogenic	uncertain significance
	pathogenic	4	1

Submitter to submitter summary #

Total submitters: 1

Download table as spreadsheet

Submitter	Variants with only 1 submission per condition	Variants with at least 2 submissions on the same condition and no conflicts	Variants with a synonymous conflict (e.g. benign vs non-pathogenic)	Variants with a confidence conflict (e.g. benign vs likely benign)	Variants with a benign or likely benign vs uncertain conflict	Variants with a category conflict (e.g. benign vs affects)	Variants with a clinically significant conflict (e.g. benign vs pathogenic)	Variants with any conflict
Foulkes Cancer Genetics LDI, Lady Davis Institute for Medical Research	0	75	0	4	0	0	1	5

All variants with conflicting interpretations #

Total variants: 5

Download table as spreadsheet

HGVS	dbSNP
NM_030621.4(DICER1):c.735-1_741delinsA	rs886037731
NM_177438.2(DICER1):c.2236A>G (p.Arg746Gly)	rs886037686
NM_177438.2(DICER1):c.4748T>G (p.Leu1583Arg)	rs137852976
NM_177438.2(DICER1):c.5123G>A (p.Gly1708Glu)	rs886037724
NM_177438.2(DICER1):c.5465A>T (p.Asp1822Val)	rs886037729

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.