ClinVar Miner

Variants with conflicting interpretations "likely benign" from Leiden Open Variation Database and "uncertain significance" from any submitter

Minimum review status of the submission from Leiden Open Variation Database: Collection method of the submission from Leiden Open Variation Database:
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Total variants with conflicting interpretations: 31
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HGVS dbSNP gnomAD frequency
NM_032444.4(SLX4):c.5501A>G (p.Asn1834Ser) rs111738042 0.00575
NM_024675.4(PALB2):c.400G>A (p.Asp134Asn) rs139555085 0.00160
NM_032444.4(SLX4):c.2359G>A (p.Glu787Lys) rs140600202 0.00125
NM_024675.4(PALB2):c.2816T>G (p.Leu939Trp) rs45478192 0.00121
NM_032444.4(SLX4):c.1372A>G (p.Lys458Glu) rs149126845 0.00087
NM_032444.4(SLX4):c.4261A>T (p.Ile1421Phe) rs141567438 0.00069
NM_000322.5(PRPH2):c.708C>T (p.Tyr236=) rs61755813 0.00062
NM_024675.4(PALB2):c.2749-18C>T rs182194007 0.00055
NM_024675.4(PALB2):c.23C>T (p.Pro8Leu) rs150390726 0.00051
NM_032444.4(SLX4):c.2681T>G (p.Val894Gly) rs145137472 0.00036
NM_032444.4(SLX4):c.3368C>A (p.Ser1123Tyr) rs144647122 0.00031
NM_024675.4(PALB2):c.1000T>G (p.Tyr334Asp) rs202241382 0.00026
NM_024675.4(PALB2):c.656A>G (p.Asp219Gly) rs45594034 0.00021
NM_024675.4(PALB2):c.3054G>C (p.Glu1018Asp) rs183489969 0.00016
NM_024675.4(PALB2):c.344G>T (p.Gly115Val) rs145598272 0.00009
NM_058216.3(RAD51C):c.7G>A (p.Gly3Arg) rs376403182 0.00003
NM_024675.4(PALB2):c.746C>T (p.Pro249Leu) rs759810283 0.00002
NM_000322.5(PRPH2):c.299C>T (p.Pro100Leu) rs768400169 0.00001
NM_005431.2(XRCC2):c.223G>C (p.Glu75Gln) rs1327414828 0.00001
NM_032444.4(SLX4):c.5081C>T (p.Ala1694Val) rs761226343 0.00001
NM_058216.3(RAD51C):c.1097G>A (p.Arg366Gln) rs577852020 0.00001
NM_058216.3(RAD51C):c.154A>C (p.Ile52Leu) rs730881927 0.00001
NM_024675.4(PALB2):c.1285A>G (p.Ile429Val) rs1555461360
NM_024675.4(PALB2):c.1376A>G (p.Asp459Gly) rs1031787378
NM_024675.4(PALB2):c.1646A>G (p.His549Arg) rs1597095334
NM_024675.4(PALB2):c.3049G>A (p.Ala1017Thr) rs759795184
NM_024675.4(PALB2):c.3053A>C (p.Glu1018Ala) rs1567212910
NM_024675.4(PALB2):c.3321G>A (p.Leu1107=) rs515726113
NM_024675.4(PALB2):c.3500C>T (p.Thr1167Ile) rs1308784980
NM_024675.4(PALB2):c.3504C>G (p.Asp1168Glu) rs1966396729
NM_032444.4(SLX4):c.421G>T (p.Gly141Trp) rs137976282

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