ClinVar Miner

Variants with conflicting interpretations "drug response" from Bruce Budowle Laboratory, University of North Texas Health Science Center and "likely benign" from any submitter

Minimum review status of the submission from Bruce Budowle Laboratory, University of North Texas Health Science Center: Collection method of the submission from Bruce Budowle Laboratory, University of North Texas Health Science Center:
Minimum review status of the other submission: Collection method of the other submission:
ClinVar version:
Total variants with conflicting interpretations: 15
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001348946.2(ABCB1):c.1236T>C (p.Gly412=) rs1128503 0.63165
NM_001348946.2(ABCB1):c.3435T>C (p.Ile1145=) rs1045642 0.57896
NM_000106.6(CYP2D6):c.1457= (p.Ser486=) rs1135840 0.42305
CYP2D6*10 rs1065852 0.18675
CYP2D6*4 rs3892097 0.14340
NM_001348946.2(ABCB1):c.61A>G (p.Asn21Asp) rs9282564 0.07388
CYP2D6*41 rs28371725 0.06736
NM_000106.6(CYP2D6):c.31G>A (p.Val11Met) rs769258 0.03995
NM_000106.6(CYP2D6):c.709G>T (p.Ala237Ser) rs28371717 0.00827
NM_000914.5(OPRM1):c.575G>T (p.Cys192Phe) rs62638690 0.00573
NM_001074.4(UGT2B7):c.137T>C (p.Leu46Pro) rs61361928 0.00284
NM_000914.5(OPRM1):c.-25C>T rs41292890 0.00226
NM_000106.6(CYP2D6):c.841_843del (p.Lys281del) rs5030656
NM_000106.6(CYP2D6):c.886= (p.Arg296=) rs16947
NM_001348946.2(ABCB1):c.2677T>G (p.Ser893Ala) rs2032582

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.