ClinVar Miner

Variants studied for Amyotrophic lateral sclerosis type 10

Coded as:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
17 11 55 9 11 16 100

Gene and significance breakdown #

Total genes and gene combinations: 9
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
TARDBP 15 10 49 9 10 16 90
ERBB4 0 0 2 0 0 0 2
MASP2, TARDBP 0 0 1 0 1 0 2
ANG, EGILA, RNASE4 0 0 1 0 0 0 1
GRN 1 0 0 0 0 0 1
LOC124629354, PRPH, TROAP 0 0 1 0 0 0 1
OPTN 0 1 0 0 0 0 1
SOD1 1 0 0 0 0 0 1
TUBA4A 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 17
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Illumina Laboratory Services, Illumina 0 0 47 9 9 0 65
GeneReviews 0 0 0 0 0 16 16
OMIM 12 0 0 0 0 0 12
Human Genetics Bochum, Ruhr University Bochum 3 3 6 0 0 0 12
Suna and Inan Kirac Foundation Neurodegeneration Research Laboratory, Koc University 1 6 0 0 0 0 7
Baylor Genetics 0 0 2 0 0 0 2
MGZ Medical Genetics Center 1 1 0 0 0 0 2
Genome Diagnostics Laboratory, University Medical Center Utrecht 0 0 0 0 2 0 2
Genome Diagnostics Laboratory, Amsterdam University Medical Center 0 0 0 1 1 0 2
Revvity Omics, Revvity 1 0 0 0 0 0 1
Institute Of Human Genetics Munich, Klinikum Rechts Der Isar, Tu München 1 0 0 0 0 0 1
SIB Swiss Institute of Bioinformatics 0 1 0 0 0 0 1
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen 0 0 1 0 0 0 1
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center 0 0 0 1 0 0 1
Codex Genetics Limited 0 1 0 0 0 0 1
Genome-Nilou Lab 0 0 0 0 1 0 1
Department of Neurology-Cell Therapy Center, Hanyang University 1 0 0 0 0 0 1

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