If a variant has more than one submission, it may be counted in more than one significance column. If this is the
    case, the total number of variants will be less than the sum of the other cells.
    
        
                | pathogenic | 
                likely pathogenic | 
                uncertain significance | 
                likely benign | 
                benign | 
                not provided | 
            total | 
        
    
    
        
                        | 
                            
                                1
                            
                         | 
                        
                            
                                2
                            
                         | 
                        
                            
                                39
                            
                         | 
                        
                            
                                2
                            
                         | 
                        
                            
                                40
                            
                         | 
                        
                            
                                1
                            
                         | 
                    
                        
                            85
                        
                     | 
        
    
Gene and significance breakdown #
            
        
    Total genes and gene combinations: 1
    
 
    
        
            | Gene or gene combination | 
                pathogenic | 
                likely pathogenic | 
                uncertain significance | 
                likely benign | 
                benign | 
                not provided | 
            total | 
        
    
    
            
                    | 
                        
                            PLEC
                        
                     | 
                            
                                
                                    1
                                
                             | 
                            
                                
                                    2
                                
                             | 
                            
                                
                                    39
                                
                             | 
                            
                                
                                    2
                                
                             | 
                            
                                
                                    40
                                
                             | 
                            
                                
                                    1
                                
                             | 
                    
                        
                            85
                        
                     | 
            
    
Submitter and significance breakdown #
            
        
    
        
            | Submitter | 
                pathogenic | 
                likely pathogenic | 
                uncertain significance | 
                likely benign | 
                benign | 
                not provided | 
            total | 
        
    
    
            
                    | 
                        
                            Genome-Nilou Lab
                        
                     | 
                            0 | 
                            0 | 
                            0 | 
                            0 | 
                            
                                
                                    39
                                
                             | 
                            0 | 
                    
                        
                            39
                        
                     | 
            
            
                    | 
                        
                            Baylor Genetics
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    8
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            8
                        
                     | 
            
            
                    | 
                        
                            Centre for Mendelian Genomics, University Medical Centre Ljubljana
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    6
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            6
                        
                     | 
            
            
                    | 
                        
                            Neuberg Centre For Genomic Medicine, NCGM
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    6
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            6
                        
                     | 
            
            
                    | 
                        
                            HudsonAlpha Institute for Biotechnology, HudsonAlpha Institute for Biotechnology
                        
                     | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            
                                
                                    2
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            4
                        
                     | 
            
            
                    | 
                        
                            Al Jalila Children’s Genomics Center, Al Jalila Childrens Speciality Hospital
                        
                     | 
                            0 | 
                            0 | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            
                                
                                    1
                                
                             | 
                            0 | 
                    
                        
                            3
                        
                     | 
            
            
                    | 
                        
                            MGZ Medical Genetics Center
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            2
                        
                     | 
            
            
                    | 
                        
                            Centogene AG  - the Rare Disease Company
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            2
                        
                     | 
            
            
                    | 
                        
                            Lupski Lab, Baylor-Hopkins CMG, Baylor College of Medicine
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            2
                        
                     | 
            
            
                    | 
                        
                            Ege University Pediatric Genetics, Ege University
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            2
                        
                     | 
            
            
                    | 
                        
                            Kariminejad - Najmabadi Pathology & Genetics Center
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            2
                        
                     | 
            
            
                    | 
                        
                            Johns Hopkins Genomics, Johns Hopkins University
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    2
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            2
                        
                     | 
            
            
                    | 
                        
                            OMIM
                        
                     | 
                            
                                
                                    1
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            1
                        
                     | 
            
            
                    | 
                        
                            Mayo Clinic Laboratories, Mayo Clinic
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    1
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            1
                        
                     | 
            
            
                    | 
                        
                            Knight Diagnostic Laboratories, Oregon Health and Sciences University
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    1
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            1
                        
                     | 
            
            
                    | 
                        
                            Foundation for Research in Genetics and Endocrinology, FRIGE's Institute of Human Genetics
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    1
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            1
                        
                     | 
            
            
                    | 
                        
                            Bioscientia Institut fuer Medizinische Diagnostik GmbH, Sonic Healthcare
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    1
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            1
                        
                     | 
            
            
                    | 
                        
                            GenomeConnect, ClinGen
                        
                     | 
                            0 | 
                            0 | 
                            0 | 
                            0 | 
                            0 | 
                            
                                
                                    1
                                
                             | 
                    
                        
                            1
                        
                     | 
            
            
                    | 
                        
                            Molecular Genetics, Royal Melbourne Hospital
                        
                     | 
                            0 | 
                            0 | 
                            
                                
                                    1
                                
                             | 
                            0 | 
                            0 | 
                            0 | 
                    
                        
                            1
                        
                     | 
            
    
 
            
                
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