ClinVar Miner

Variants studied for Breast-ovarian cancer, familial, susceptibility to, 4

Coded as:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
142 103 692 465 25 6 6 1362

Gene and significance breakdown #

Total genes and gene combinations: 5
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
RAD51D, RAD51L3-RFFL 126 100 685 464 24 6 6 1334
RAD51D 16 3 5 0 0 0 0 24
LOC130060715, RAD51D, RAD51L3-RFFL 0 0 0 1 1 0 0 2
FNDC8 0 0 1 0 0 0 0 1
FNDC8, LOC130060715, RAD51D, RAD51L3-RFFL 0 0 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 28
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Invitae 98 50 644 439 22 0 0 1253
Myriad Genetics, Inc. 75 43 22 10 9 0 0 159
Baylor Genetics 19 17 93 1 0 0 0 130
Counsyl 6 13 23 27 4 0 0 73
Mendelics 1 4 14 12 0 0 0 31
Hereditary Cancer Group, L’Institut d'Investigació Biomèdica de Bellvitge 10 6 5 1 0 0 0 22
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 1 1 6 8 4 0 0 20
Fulgent Genetics, Fulgent Genetics 5 2 10 1 0 0 0 18
MGZ Medical Genetics Center 2 2 10 0 0 0 0 14
Institute of Human Genetics, University of Leipzig Medical Center 3 1 5 0 1 0 0 10
OMIM 0 0 0 0 0 6 0 6
Department of Pathology and Laboratory Medicine, Sinai Health System 2 1 3 0 0 0 0 6
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 2 3 0 0 0 0 5
Genetics and Molecular Pathology, SA Pathology 0 0 4 0 0 0 0 4
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 0 4 4
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 1 0 3 0 0 0 0 4
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 0 1 2 0 0 0 0 3
Neuberg Centre For Genomic Medicine, NCGM 1 0 2 0 0 0 0 3
GenomeConnect, ClinGen 0 0 0 0 0 0 2 2
Department of Human Genetics, Hannover Medical School 0 0 2 0 0 0 0 2
BRCAlab, Lund University 1 1 0 0 0 0 0 2
Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center 0 1 0 0 0 0 0 1
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 1 0 0 0 0 0 0 1
Department of Molecular Diagnostics, Institute of Oncology Ljubljana 0 1 0 0 0 0 0 1
University of Washington Department of Laboratory Medicine, University of Washington 0 0 0 1 0 0 0 1
Division of Medical Genetics, University of Washington 0 0 1 0 0 0 0 1
Dr. med. U. Finckh, Human Genetics, Eurofins MVZ 0 0 1 0 0 0 0 1
Human Genetics Bochum, Ruhr University Bochum 0 1 0 0 0 0 0 1

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