Variants studied for Classic or attenuated familial adenomatous polyposis

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
53	16	1330	515	18	1926

Gene and significance breakdown #

Total genes and gene combinations: 2

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
APC	53	11	1326	515	18	1917
APC, LOC129994371	0	5	4	0	0	9

Submitter and significance breakdown #

Total submitters: 3

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
All of Us Research Program, National Institutes of Health	36	10	1297	504	14	1861
Department of Pathology and Laboratory Medicine, Sinai Health System	18	6	60	19	4	107
ClinGen InSiGHT Hereditary Colorectal Cancer/Polyposis Variant Curation Expert Panel	0	0	3	0	0	3

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