If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
90
|
65
|
247
|
340
|
81
|
17
|
799
|
Gene and significance breakdown #
Total genes and gene combinations: 7
Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
SLC6A1
|
86
|
63
|
247
|
340
|
81
|
17
|
793
|
ARPC4, ARPC4-TTLL3, ATP2B2, BRK1, BRPF1, CAMK1, CIDEC, CPNE9, CRELD1, EMC3, FANCD2, FANCD2OS, GHRL, GHRLOS, IL17RC, IL17RE, IRAK2, JAGN1, MTMR14, OGG1, PRRT3, RPUSD3, SEC13, SLC6A1, SLC6A11, TADA3, TATDN2, TTLL3, VHL
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
ATP2B2, BRK1, CRELD1, EMC3, FANCD2, FANCD2OS, GHRL, GHRLOS, IL17RC, IRAK2, PRRT3, SEC13, SLC6A1, SLC6A11, TATDN2, VHL
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
ATP2B2, BRK1, FANCD2, FANCD2OS, GHRL, GHRLOS, IRAK2, SEC13, SLC6A1, SLC6A11, TATDN2, VHL
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
CHD2
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
SEMA6B
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
SLC2A1
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Submitter and significance breakdown #
Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
Labcorp Genetics (formerly Invitae), Labcorp
|
71
|
19
|
213
|
335
|
81
|
0 |
719
|
Institute of Human Genetics, University of Leipzig Medical Center
|
5
|
6
|
7
|
0 |
0 |
0 |
18
|
GenomeConnect - Brain Gene Registry
|
0 |
0 |
0 |
0 |
0 |
15
|
15
|
Revvity Omics, Revvity
|
2
|
1
|
9
|
0 |
0 |
0 |
12
|
Génétique des Maladies du Développement, Hospices Civils de Lyon
|
3
|
6
|
1
|
1
|
0 |
0 |
11
|
Mendelics
|
2
|
5
|
1
|
0 |
0 |
0 |
8
|
Fulgent Genetics, Fulgent Genetics
|
2
|
0 |
3
|
3
|
0 |
0 |
8
|
New York Genome Center
|
1
|
1
|
6
|
0 |
0 |
0 |
8
|
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute
|
4
|
3
|
0 |
0 |
0 |
0 |
7
|
OMIM
|
5
|
0 |
0 |
0 |
0 |
0 |
5
|
3billion, Medical Genetics
|
1
|
2
|
1
|
1
|
0 |
0 |
5
|
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre
|
0 |
0 |
3
|
1
|
0 |
0 |
4
|
Solve-RD Consortium
|
0 |
4
|
0 |
0 |
0 |
0 |
4
|
Baylor Genetics
|
1
|
1
|
1
|
0 |
0 |
0 |
3
|
Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center
|
1
|
2
|
0 |
0 |
0 |
0 |
3
|
MGZ Medical Genetics Center
|
0 |
2
|
1
|
0 |
0 |
0 |
3
|
Institute of Human Genetics Munich, Klinikum Rechts Der Isar, TU München
|
2
|
1
|
0 |
0 |
0 |
0 |
3
|
Institute of Human Genetics, Clinical Exome/Genome Diagnostics Group, University Hospital Bonn
|
1
|
2
|
0 |
0 |
0 |
0 |
3
|
Neuberg Centre For Genomic Medicine, NCGM
|
0 |
0 |
3
|
0 |
0 |
0 |
3
|
Center For Human Genetics And Laboratory Diagnostics, Dr. Klein, Dr. Rost And Colleagues
|
1
|
0 |
1
|
0 |
0 |
0 |
2
|
Equipe Genetique des Anomalies du Developpement, Université de Bourgogne
|
0 |
2
|
0 |
0 |
0 |
0 |
2
|
Juno Genomics, Hangzhou Juno Genomics, Inc
|
0 |
2
|
0 |
0 |
0 |
0 |
2
|
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Illumina Laboratory Services, Illumina
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Institute for Human Genetics and Genomic Medicine, Uniklinik RWTH Aachen
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Duke University Health System Sequencing Clinic, Duke University Health System
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
HudsonAlpha Institute for Biotechnology, HudsonAlpha Institute for Biotechnology
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Centre de Biologie Pathologie Génétique, Centre Hospitalier Universitaire de Lille
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Medical Genetic Institute of Henan Province, Henan Provincial People’s Hospital
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Neurogenetics Laboratory - MEYER, AOU Meyer
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Groupe Hospitalier Pitie Salpetriere, UF Genomique du Developpement, Assistance Publique Hopitaux de Paris
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
GenomeConnect, ClinGen
|
0 |
0 |
0 |
0 |
0 |
1
|
1
|
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Biochemical Molecular Genetic Laboratory, King Abdulaziz Medical City
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Molecular Diagnostics Laboratory, M Health Fairview: University of Minnesota
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Genomic Medicine Lab, University of California San Francisco
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Department of Genetics, Rouen University Hospital, Normandy Center for Genomic and Personalized Medicine
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Cytoplasmic Inheritance Laboratory, Institute of Genetics and Cytology
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Genetics Laboratory - UDIAT Centre Diagnòstic, Hospital Universitari Parc Tauli
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Unidad de Genómica Garrahan, Hospital de Pediatría Garrahan
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Diagnostic Genetics, Severance Hospital, Yonsei University College of Medicine
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Pediatric Department, Xiangya Hospital, Central South University
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Concord Molecular Medicine Laboratory, Concord Repatriation General Hospital
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Provincial Medical Genetics Program of British Columbia, University of British Columbia
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Institute of Immunology and Genetics Kaiserslautern
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
Department of Developmental Neurology, Medical University of Gdańsk
|
0 |
0 |
0 |
0 |
0 |
1
|
1
|
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