Variants studied for Familial multiple polyposis syndrome

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
99	50	16	7	9	181

Gene and significance breakdown #

Total genes and gene combinations: 3

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
APC	98	50	15	7	7	177
MUTYH	0	0	1	0	2	3
APC, LOC121079956, LOC129994371	1	0	0	0	0	1

Submitter and significance breakdown #

Total submitters: 12

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
Women's Health and Genetics/Laboratory Corporation of America, LabCorp	56	38	0	0	0	94
Department of Pathology and Laboratory Medicine, Sinai Health System	29	0	0	0	3	32
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine	14	8	0	0	0	22
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics, Children's Hospital of Philadelphia	0	0	9	1	6	16
Center for Human Genetics, Inc, Center for Human Genetics, Inc	7	3	3	1	0	14
CSER _CC_NCGL, University of Washington	0	0	4	2	0	6
University of Washington Department of Laboratory Medicine, University of Washington	0	0	0	3	0	3
Department of Clinical Genetics, Copenhagen University Hospital, Rigshospitalet	1	0	0	0	0	1
Rady Children's Institute for Genomic Medicine, Rady Children's Hospital San Diego	1	0	0	0	0	1
3DMed Clinical Laboratory Inc	1	0	0	0	0	1
Molecular Diagnostics Laboratory, M Health Fairview: University of Minnesota	0	1	0	0	0	1
St. Jude Molecular Pathology, St. Jude Children's Research Hospital	0	0	1	0	0	1

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