If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
total |
34
|
27
|
122
|
138
|
19
|
336
|
Gene and significance breakdown #
Total genes and gene combinations: 5
Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
total |
STX1B
|
30
|
27
|
120
|
138
|
19
|
330
|
HSD3B7, STX1B
|
1
|
0 |
1
|
0 |
0 |
2
|
LOC130058887, STX1B
|
2
|
0 |
0 |
0 |
0 |
2
|
BCL7C, CFAP119, CTF1, FBXL19, HSD3B7, ORAI3, PHKG2, RNF40, SETD1A, SRCAP, STX1B, ZNF629
|
0 |
0 |
1
|
0 |
0 |
1
|
LOC130058885, LOC130058886, LOC130058887, STX1B, STX4, ZNF668
|
1
|
0 |
0 |
0 |
0 |
1
|
Submitter and significance breakdown #
Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
total |
Labcorp Genetics (formerly Invitae), Labcorp
|
24
|
18
|
113
|
137
|
18
|
310
|
OMIM
|
5
|
0 |
0 |
0 |
0 |
5
|
Institute of Human Genetics, University of Leipzig Medical Center
|
1
|
2
|
2
|
0 |
0 |
5
|
Baylor Genetics
|
0 |
0 |
4
|
0 |
0 |
4
|
Fulgent Genetics, Fulgent Genetics
|
0 |
1
|
1
|
2
|
0 |
4
|
Genome-Nilou Lab
|
0 |
0 |
0 |
0 |
3
|
3
|
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories
|
0 |
0 |
0 |
1
|
1
|
2
|
Revvity Omics, Revvity
|
0 |
0 |
2
|
0 |
0 |
2
|
Institute of Human Genetics Munich, Klinikum Rechts Der Isar, TU München
|
1
|
1
|
0 |
0 |
0 |
2
|
MGZ Medical Genetics Center
|
0 |
0 |
1
|
0 |
0 |
1
|
Mendelics
|
0 |
1
|
0 |
0 |
0 |
1
|
Institute for Human Genetics and Genomic Medicine, Uniklinik RWTH Aachen
|
0 |
0 |
1
|
0 |
0 |
1
|
Centre for Mendelian Genomics, University Medical Centre Ljubljana
|
0 |
0 |
1
|
0 |
0 |
1
|
Equipe Genetique des Anomalies du Developpement, Université de Bourgogne
|
1
|
0 |
0 |
0 |
0 |
1
|
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen
|
0 |
0 |
1
|
0 |
0 |
1
|
Génétique des Maladies du Développement, Hospices Civils de Lyon
|
1
|
0 |
0 |
0 |
0 |
1
|
New York Genome Center
|
0 |
0 |
1
|
0 |
0 |
1
|
Diagnostic Genetics, Severance Hospital, Yonsei University College of Medicine
|
0 |
1
|
0 |
0 |
0 |
1
|
Pediatrics, MediClubGeorgia
|
0 |
1
|
0 |
0 |
0 |
1
|
3billion, Medical Genetics
|
1
|
0 |
0 |
0 |
0 |
1
|
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein
|
1
|
0 |
0 |
0 |
0 |
1
|
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein
|
0 |
1
|
0 |
0 |
0 |
1
|
Solve-RD Consortium
|
0 |
1
|
0 |
0 |
0 |
1
|
The information on this website is not intended for direct
diagnostic use or medical decision-making without review by a
genetics professional. Individuals should not change their
health behavior solely on the basis of information contained on
this website. Neither the University of Utah nor the National
Institutes of Health independently verfies the submitted
information. If you have questions about the information
contained on this website, please see a health care
professional.