Variants studied for Meier-Gorlin syndrome 1

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
12	5	43	8	11	1	77

Gene and significance breakdown #

Total genes and gene combinations: 3

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
ORC1	12	4	41	8	11	1	74
DONSON	0	1	1	0	0	0	2
LOC126805733, ORC1	0	0	1	0	0	0	1

Submitter and significance breakdown #

Total submitters: 14

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
Illumina Laboratory Services, Illumina	0	1	37	7	11	0	56
OMIM	7	0	0	0	0	0	7
Baylor Genetics	1	1	2	0	0	0	4
Revvity Omics, Revvity	2	0	1	0	0	0	3
Fulgent Genetics, Fulgent Genetics	0	0	0	3	0	0	3
Bicknell laboratory, University of Otago	3	0	0	0	0	0	3
Institute of Human Genetics, University of Goettingen	0	1	1	0	0	0	2
Al Jalila Children's Genomics Center, Al Jalila Childrens Speciality Hospital	0	0	1	0	1	0	2
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	0	0	1	0	0	0	1
Mayo Clinic Laboratories, Mayo Clinic	0	0	1	0	0	0	1
Genomic Research Center, Shahid Beheshti University of Medical Sciences	0	0	1	0	0	0	1
Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences	0	1	0	0	0	0	1
GenomeConnect, ClinGen	0	0	0	0	0	1	1
Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Peking Union Medical College Hospital	0	1	0	0	0	0	1

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